Characterization and use of a gamma radiation TLC scanner for radiochemical purity measurements of radiopharmaceutical kit preparations of99mTc(dmpe)2Cl 2+

A. Carpenter; T. Mysliwy; S. Sivakoff; M. Doshi; E. Wolshin; M. Matthew; G. Schnaper; V. Subramanyam; L. Camin

doi:10.1007/bf02040607

Journal of Radioanalytical and Nuclear Chemistry

Volume/Issue:: Volume 89: Issue 2

Characterization and use of a gamma radiation TLC scanner for radiochemical purity measurements of radiopharmaceutical kit preparations of^99mTc(dmpe)₂Cl ₂⁺

Authors:

A. Carpenter

A. Carpenter New England Nuclear, Radiopharmaceuticals Research Department 331 Treble Cove Road 01862 N. Billerica Mass. (USA)

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T. Mysliwy

T. Mysliwy New England Nuclear, Radiopharmaceuticals Research Department 331 Treble Cove Road 01862 N. Billerica Mass. (USA)

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S. Sivakoff

S. Sivakoff New England Nuclear, Radiopharmaceuticals Research Department 331 Treble Cove Road 01862 N. Billerica Mass. (USA)

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M. Doshi

M. Doshi New England Nuclear, Radiopharmaceuticals Research Department 331 Treble Cove Road 01862 N. Billerica Mass. (USA)

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E. Wolshin

E. Wolshin New England Nuclear, Radiopharmaceuticals Research Department 331 Treble Cove Road 01862 N. Billerica Mass. (USA)

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M. Matthew

M. Matthew New England Nuclear, Radiopharmaceuticals Research Department 331 Treble Cove Road 01862 N. Billerica Mass. (USA)

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G. Schnaper

G. Schnaper New England Nuclear, Radiopharmaceuticals Research Department 331 Treble Cove Road 01862 N. Billerica Mass. (USA)

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V. Subramanyam

V. Subramanyam New England Nuclear, Radiopharmaceuticals Research Department 331 Treble Cove Road 01862 N. Billerica Mass. (USA)

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, and

L. Camin

L. Camin New England Nuclear, Radiopharmaceuticals Research Department 331 Treble Cove Road 01862 N. Billerica Mass. (USA)

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Pages:: 435–446

Online Publication Date:: 14 Aug 2005

Publication Date:: 17 Apr 1985

Article Category:: Research Article

DOI:: https://doi.org/10.1007/bf02040607

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Abstract

A simple, low cost TLC scanner system for the characterization of -emitting radiopharmaceuticals is described. The TLC scanner has a linear response range of 0.074 Mbq up to 2.94 Mbq. The accuracy and reproducibility of measurement is better than ±5% (relative). The utility of this TLC scanner system is demonstrated by application to the radioanalytical evaluation of^99mTc(dmpe)₂Cl ₂⁺ preparations. A comparison with HPLC radioanalytical separations is made.

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Journal of Radioanalytical and Nuclear Chemistry

Print ISSN:: 0236-5731

Online ISSN:: 1588-2780

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Journal of Radionalytical and Nuclear Chemistry
Language	English
Size	A4
Year of Foundation	1968
Volumes per Year	1
Issues per Year	12
Founder	Akadémiai Kiadó
Founder's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher	Akadémiai Kiadó Springer Nature Switzerland AG
Publisher's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible Publisher	Chief Executive Officer, Akadémiai Kiadó
ISSN	0236-5731 (Print)
ISSN	1588-2780 (Online)