Authors:
F. Helus German Cancer Research Center Institut of Nuclear Medicine Neuenheimer Feld 280 D-6900 Heidelberg (FRG)

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W. Maier-Borst German Cancer Research Center Institut of Nuclear Medicine Neuenheimer Feld 280 D-6900 Heidelberg (FRG)

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H. Bauer German Cancer Research Center Institut of Nuclear Medicine Neuenheimer Feld 280 D-6900 Heidelberg (FRG)

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L. Wiebe University of Alberta Bionucleonics and Radiopharmacy Edmonton (Canada)

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Abstract  

The cyclotron production of21Na, via the20Ne(d, n)21Na and the20Ne(3He, pn)21Na and20Ne(3He, 2n)21Mg 21Na nuclear reactions, has been investigated. Transfer of21Na from the production target to the medical application site some 10 m distant was achieved by gas phase and liquid phase systems, both of which are described. Under optimal conditions 111 MBq·ml–1 (3 mCi·ml–1) of21Na were available at the dispensing reservoir 10 m distant from the production target, when irradiating with a 5 A deuteron beam current. Incident deuteron energy was degraded to below 3.0 MeV by a 350 m Al entrance foil, to avoid production of18F. The charge distribution of21Na inside the production target and inside the gas phase transfer tube at distances of 1 m and 15 m were determined, and are reported along with data from similar studies during18F production via the20Ne(d, )18F reaction.21Na accumulated primarily at the cathode, indicating the production of positively charged species, whereas18F was equally distributed between the electrodes in a production target constructed especially for measuring the charge distribution of the radioactive species.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)