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  • 1 Netherlands Energy Research Foundation P.O. Box 1 1755 ZG Petten (The Netherlands)
  • | 2 Free University Analytical Chemistry Laboratory De Boelelaan 1083 1081 HV Amsterdam (The Netherlands)
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Abstract  

The use of on-line -detection in HPLC of radioactive-labelled samples is hampered by the time lag between the (relatively) fast separation and the slow counting. In the present approach, this difficulty is overcome by introducing a storage loop in which the eluate is temporarily stored, interspaced by a non-mixing liquid which may be the scintillator itself. The apparatus developed enables the determination of radiochromatograms which contain a total activity of 10 Bq.