Authors:
S. Gonella UC2M2, EA3233, Université de Rouen, rue Tesnière, 76821, Mont Saint Aignan Cedex, France

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G. Levilain UC2M2, EA3233, Université de Rouen, rue Tesnière, 76821, Mont Saint Aignan Cedex, France

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G. Coquerel UC2M2, EA3233, Université de Rouen, rue Tesnière, 76821, Mont Saint Aignan Cedex, France

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Abstract

Heterogeneous equilibria are reviewed in binary and ternary systems of enantiomers without and with in situ racemization. The twofold symmetry between the two chiral components is also found in the phase diagrams except for stable conglomerate forming systems associated with a fast in situ racemization in the liquid phase. In this particular case, a gentle attrition speeds up the irreversible evolution of the system towards a spontaneous symmetry breaking, i.e., a single crystallized enantiomer in equilibrium with its racemic solution. This final evolution is predicted to reach the limit of miscibility in the solid state for conglomerate forming system with partial solid solution and in situ racemization.

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  • 3. Noorduin, WL, Vlieg, E, Kellogg, RM, Kaptein, B. From Ostwald ripening to single chirality. Angew Chem Int Ed 2009 48:96009606.

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
1
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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