Journal of Thermal Analysis and Calorimetry
Volume/Issue:
Volume 103: Issue 1
Water evaporation from gel beads
A calorimetric approach to hydrogel matrix release properties
Authors:
Barbara Bellich Laboratory of Physical and Macromolecular Chemistry, Department of Life Sciences, University of Trieste, via l. Giorgieri, 1-34127, Trieste, Italy

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Massimiliano Borgogna Laboratory of Physical and Macromolecular Chemistry, Department of Life Sciences, University of Trieste, via l. Giorgieri, 1-34127, Trieste, Italy

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Michela Cok Laboratory of Physical and Macromolecular Chemistry, Department of Life Sciences, University of Trieste, via l. Giorgieri, 1-34127, Trieste, Italy

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Attilio Cesàro Laboratory of Physical and Macromolecular Chemistry, Department of Life Sciences, University of Trieste, via l. Giorgieri, 1-34127, Trieste, Italy

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Pages:
81–88
Online Publication Date:
15 Dec 2010
Publication Date:
01 Jan 2011
Article Category:
Research Article
DOI:
https://doi.org/10.1007/s10973-010-1170-5
Keywords:
DSC; Water effusion; Hydrogel; Beads; Release
Restricted access

Abstract

Hydrogels are characterized by properties which make them ideal candidates for applications in several fields, such as drug delivery, biomedicine, and functional foods. Molecular diffusion out of a hydrogel matrix depends on their hydrodynamic radii and the mesh sizes within the matrix of the gel. A quantitative experimental and mathematical understanding of interactions, kinetics, and transport phenomena within complex hydrogel systems assists network design by identifying the key parameters and mechanisms that govern the rate and extent of solute release. In this article a calorimetric differential scanning calorimetry (DSC) study reports on the approach to parallel water effusion from a hydrogel matrix to the release of a model protein. The measurement of the water evaporation is taken as the simplest routine determination of a phenomenon that is basically due to a diffusive process through the porous structure of the gel and thermodynamically governed by the difference in the water chemical potential inside and outside of the bead. The analysis of the experimental calorimetric curves is made with the purpose of extracting several numerical parameters characteristic of each curve. The rationale is to develop a simple methodology to understand the release properties of the porous structure of the complex gel matrix by means of DSC.

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Cover Journal of Thermal Analysis and Calorimetry
Journal of Thermal Analysis and Calorimetry
Print ISSN:
1388-6150
Online ISSN:
1572-8943

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation		 1969
Volumes
per Year		 1
Issues
per Year		 24
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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