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  • 1 Faculty of Physics, Babes-Bolyai University, Cluj-Napoca, Romania
  • | 2 National Institute for R&D of Isotopic and Molecular Technologies, P.O. Box 700, 400293, Cluj-Napoca, Romania
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Abstract

Ambazone, a well-known antimicrobial compound, presents also oncostatic properties. The solid form, obtained by using solvent-drop grinding procedure, was characterized by using several physical techniques such as FTIR, X-ray photoelectron spectroscopy, 13C NMR and 15N NMR spectroscopies, thermal analysis, X-ray powder diffraction and mass spectrometry. Based on these data, it was demonstrated that an ambazone–hydrochloride was obtained: new vibrations corresponding to NH2+ were identified. DTA–TG–DSC and MS data revealed that a new crystal type has been obtained. X-ray diffraction data allowed the determination of the lattice parameters and the most probable space group P21/c was established also with only one molecule per asymmetric unit.

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