Journal of Thermal Analysis and Calorimetry
Volume/Issue:
Volume 106: Issue 2
Vitamin A and vitamin E interaction behavior on chitosan microspheres
A calorimetric view
Authors:
Alexandre G. S. Prado QuiCSI Team, Institute of Chemistry, University of Brasilia, C.P. 4478, Brasilia, DF, 70904-970, Brazil

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André L. F. Santos QuiCSI Team, Institute of Chemistry, University of Brasilia, C.P. 4478, Brasilia, DF, 70904-970, Brazil

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Carolina P. Pedroso QuiCSI Team, Institute of Chemistry, University of Brasilia, C.P. 4478, Brasilia, DF, 70904-970, Brazil

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Thiago O. Carvalho QuiCSI Team, Institute of Chemistry, University of Brasilia, C.P. 4478, Brasilia, DF, 70904-970, Brazil

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Lilian R. Braga QuiCSI Team, Institute of Chemistry, University of Brasilia, C.P. 4478, Brasilia, DF, 70904-970, Brazil

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Sheila M. Evangelista QuiCSI Team, Institute of Chemistry, University of Brasilia, C.P. 4478, Brasilia, DF, 70904-970, Brazil

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Pages:
415–420
Online Publication Date:
04 Mar 2011
Publication Date:
01 Nov 2011
Article Category:
Research Article
DOI:
https://doi.org/10.1007/s10973-011-1418-8
Keywords:
Calorimetry; Chitosan; Vitamins
Restricted access

Abstract

Chitosan is a biodegradable natural polymer with great potential for pharmaceutical applications due to its biocompatibility, high charge density, and non-toxicity. In this study, chitosan microspheres were successfully prepared by an adapted method of coagulation/dispersion. The degree of deacetylation of chitosan powder was obtained by NMR 1H and FTIR techniques. Chitosan powder and chitosan microspheres were characterized by BET surface area and scanning electron microscopy (SEM). The interactions among the chitosan microspheres and the vitamins A and E were characterized by FTIR. In order to evaluate the ability of interaction of vitamin A and vitamin E with the chitosan microspheres, the thermodynamic parameters were followed by calorimetric titration. Different experimental approaches were applied, such as adsorption isotherms, kinetics and thermodynamics studies. The obtained results showed that the interactions of chitosan microspheres with the vitamins were spontaneous, enthalpically and entropically favorable, indicating that the chitosan microspheres can be used with success in the controlled release of these vitamins.

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Cover Journal of Thermal Analysis and Calorimetry
Journal of Thermal Analysis and Calorimetry
Print ISSN:
1388-6150
Online ISSN:
1572-8943

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation		 1969
Volumes
per Year		 1
Issues
per Year		 24
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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