View More View Less
  • 1 College of Textiles, Donghua University, No. 2999 North Renmin Rd., Songjiang, Shanghai 201620, China
Restricted access

Abstract

Poly(caprolactone) (PCL) is one of biodegradable and biocompatible polymers, which have received significant attention because they are environmentally friendly and are extensively used in biomedical applications. Electrospinning was a straightforward method to produce nanofibers from polymer solutions in a wide submicron range around 100 nm. However, no clear standard had been established for judging whether a solvent of high solubility for a polymer would produce a solution good for electrospinning. Considering the above-mentioned cause, we explored the effect of solvent on fibrous morphology, FT–IR spectra and 1H NMR spectra, viscosity and shearing strength, differential scanning calorimetry (DSC) of PCL electrospun nonwoven membranes in this article. When NMP and AC were used as the solvent for PCL electrospinning, all of them were composed of smooth and nanosized fibers with similar fiber surface morphologies. Meanwhile, when DCM and CF were used as solvent, there were lots of holes in fibers due to high evaporation. The electrospinnability was good when CA was chosen as solvent due to its lowest viscosity.

  • 1. Reneker, DH, Yarin, AL, Fong, H, Koombhongse, S. Bending instability of electrically charged liquid jets of polymer solutions in electrospinning. J Appl Phys. 2000;87:45314548.

    • Search Google Scholar
    • Export Citation
  • 2. Ma, QA, Cebe, P. Phase structure of electrospun poly(trimethylene terephthalate) composite nanofibers containing carbon nanotubes. J Therm Anal Calorim. 2010;102:425434.

    • Search Google Scholar
    • Export Citation
  • 3. Reneker, DH, Chun, I. Nanometre diameter fibres of polymer, produced by electrospinning. Nanotechnology. 1996;7:216223.

  • 4. Qin, XH. Structure and property of electrospinning PAN nanofibers by different preoxidation temperature. J Therm Anal Calorim. 2010;99:571575.

    • Search Google Scholar
    • Export Citation
  • 5. Stephens, JS, Frisk, S, Megelski, S, Rabolt, JF, Chase, DB. “Real time” Raman studies of electrospun fibers. Appl Spectrosc. 2001;55:12871290.

    • Search Google Scholar
    • Export Citation
  • 6. Kim, HS, Lee, BH, Lee, S, Kim, HJ, Dorgan, J. Enhanced interfacial adhesion, mechanical, and thermal properties of natural flour-filled biodegradable polymer bio-composites. J Therm Anal Calorim. 2011;104:331338.

    • Search Google Scholar
    • Export Citation
  • 7. Mckee, MG, Hunley, MT, Layman, JM. Long TE solution rheological behavior and electrospinning of cationic polyelectrolytes. Macromolecules. 2006;39:575583.

    • Search Google Scholar
    • Export Citation
  • 8. Colby, RH, Fetters, LJ, Funk, WG, Graessley, WW. Effects of concentration and thermodynamic interaction on the viscoelastic properties of polymer-solutions. Macromolecules. 1991;24:38733882.

    • Search Google Scholar
    • Export Citation
  • 9. Megelski, S, Stephens, JS, Chase, DB, Rabolt, JF. Micro- and nanostructured surface morphology on electrospun polymer fibers. Macromolecules. 2002;35:84568466.

    • Search Google Scholar
    • Export Citation
  • 10. Lee, KH, Kim, HY, La, YM, Lee, DR, Sung, NH. Influence of a mixing solvent with tetrahydrofuran, N,N-dimethylformamide on electrospun poly(vinyl chloride) nonwoven mats. J Polym Sci B Polym Phys. 2002;40:22592268.

    • Search Google Scholar
    • Export Citation
  • 11. Fong, H, Chun, I, Reneker, DH. Beaded nanofibers formed during electrospinning. Polymer. 1999;40:45854592.

  • 12. Olaru, N, Olaru, L. Electrospinning of cellulose acetate phthalate from different solvent systems. Ind Eng Chem Res. 2010;49:19531957.

    • Search Google Scholar
    • Export Citation
  • 13. Luo, CJ, Nangrejo, M, Edirisinghe, M. A novel method of selecting solvents for polymer electrospinning. Polymer. 2010;51:16541662.

    • Search Google Scholar
    • Export Citation
  • 14. Romeo, V, Gorrasi, G, Vittoria, V. Encapsulation and exfoliation of inorganic lamellar fillers into polycaprolactone by electrospinning. Biomacromolecules. 2007;8:31473152.

    • Search Google Scholar
    • Export Citation
  • 15. Hirose, S, Hatakeyama, T, Izuta, Y, Hatakeyama, H. TG-FTIR studies on lignin-based polycaprolactones. J Therm Anal Calorim. 2002;70:853860.

    • Search Google Scholar
    • Export Citation
  • 16. Szamel, G, Klebert, S, Sajo, I, Pukanszky, B. Thermal analysis of cellulose acetate modified with caprolactone. J Therm Anal Calorim. 2008;91:715722.

    • Search Google Scholar
    • Export Citation
  • 17. Del Gaudio, C, Bianco, A, Folin, M, Baiguera, S, Grigioni, M. Structural characterization and cell response evaluation of electrospun PCL membranes: micrometric versus submicrometric fibers. J Biomed Mater Res A. 2009;89:10281039.

    • Search Google Scholar
    • Export Citation
  • 18. Deitzel, JM, Kleinmeyer, JD, Harris, D, Tan, NC. The effect of processing variables on the morphology of electrospun nanofibers and textiles. Polymer. 2001;42:261272.

    • Search Google Scholar
    • Export Citation
  • 19. Reneker DH , Yarin A, Zussman E, Koombhongse S, Kataphinan W. Nanofiber manufacturing: toward better process control. In: Reneker DH, Fong H, editors. Washington, DC: ACS Symposium Series; 2006. p. 720.

    • Search Google Scholar
    • Export Citation
  • 20. Zong, X, Kim, K, Fang, D, Ran, S, Hsiao, BJ, Chu, B. Structure and process relationship of electrospun bioabsorbable nanofiber membranes. Polymer. 2002;43:44034412.

    • Search Google Scholar
    • Export Citation