Authors:
Z. X. Li Department of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji 721013, Shaanxi, People's Republic of China

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X. H. Pu Department of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji 721013, Shaanxi, People's Republic of China

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W. W. Zhao Department of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji 721013, Shaanxi, People's Republic of China

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Abstract

Laburnine's dissolution behaviors in glucose and saline solution were studied by a micro-calorimetry method. The measured integral and differential heats of solution were utilized to build equations of the solute and the heat, so that dissolution thermodynamic equations and half-time periods, ΔsolHm, ΔsolGm, and ΔsolSm were obtained. The results show that this study does not only provide a simple method for the determination of the half-life period for a drug but also offer a theoretical reference for the clinical application of laburnine.

  • 1. Amroyan, EA. Participation of type “E” prostaglandins in the effects of cytosine on cerebral vessel resistance. Eksp Klin Med. 1977;17:37.

    • Search Google Scholar
    • Export Citation
  • 2. Wei, QH, Zhao, BG. Alkaloids of Thermopsis lanceolata R. Brown and their biological activities. J Nanjing For Univ (Nat Sci Ed). 2000;24:7375. (in Chinese).

    • Search Google Scholar
    • Export Citation
  • 3. Wang, JX, Wang, GJ. Progress on pharmacology and clinical application of matrine and oxymatrine. Chin Hepatol. 2000;5:116117.

  • 4. Sun, XJ, Xu, XY, Liu, M, Li, LW, Sun, DZ. Enthalpic interactions of anti-tumor drug matrine in aqueous sodium chloride solutions. J Therm Anal Calorim. 2010;100:10731077. .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 5. Li, ZX, Pu, XH, Zhao, WW. Dissolution properties of oxymatrine in citric acid solution. J Therm Anal Calorim. 2011;104:11911194. .

  • 6. Montgomery, RL, Melaugh, RA, Lau, CC, Meier, GH, Chan, HH, Rossini, FD. Determination of the energy equivalent of a water solution calorimeter with a standard substance. J Chem Thermodyn. 1977;9:915936. .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 7. Xue, L, Zhao, FQ, Xing, XL. Dissolution properties of 1,3,3-trinitroazetidine in ethyl acetate and N,N-dimethylformamide. Acta Phys Chim Sin. 2009;25:24132416.

    • Search Google Scholar
    • Export Citation
  • 8. Gao, SL, Chen, SP, Hu, RZ, Li, HY, Shi, QZ. Derivation and application of theromodynamic equations. Chin J Inorg Chem. 2002;18:362366. (in Chinese).

    • Search Google Scholar
    • Export Citation
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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
1
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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