The thermal decomposition of a new antibiotic agent, cefuroxime lysine, was investigated by thermogravimetry analysis/derivative thermogravimetry and differential scanning calorimetry (DSC) methods in anoxic and oxidative environments. The influence of heating rates (including 5, 10, 15, and 20 °C/min) on the thermal behavior of cefuroxime lysine was revealed. By the methods of Kissinger and Flynn–Wall–Ozawa, the thermal kinetic parameters of activation energy and pre-exponential factor for the exothermic processes under non-isothermal conditions were calculated using the analysis of corresponding DSC curves.
Humienik, MO, Mozejko, J. Thermodynamic functions of activated complexes created in thermal decomposition processes of sulphates. Thermochim Acta. 2000;344:73–79. 10.1016/S0040-6031(99)00329-9.)| false