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  • 1 Department of Chemistry and Environment Engineering, Wuhan Bioengineering Institute, Wuhan 430415, Hubei, China
  • | 2 College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, Hubei, China
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Abstract

The thermal behaviors of enoxacin and its hydrochloride under inert conditions were investigated by TG, FTIR, and TG/DSC-FTIR. The results indicated that the thermal behavior of enoxacin can be divided into three stages, while its hydrochloride consisted of four stages. The main difference lay in the sequence of decarboxylation and decarbonylation. For the enoxacin, the decarboxylation and decarbonylation occurred simultaneously, but for its hydrochloride, the two processes occurred in turn. The reason for this was the existence of hydrochloric acid in enoxacin hydrochloride, which changed its intermolecular force. The thermal analysis kinetic calculations of their first two stages were carried out, respectively. The apparent activation energy, pre-exponential factor, and the most probable model function were obtained using the master plots method. The results indicated that all these stages can be described by the model of nucleation and nucleus growing.

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Manuscript Submission: HERE

  • Impact Factor (2019): 2.731
  • Scimago Journal Rank (2019): 0.415
  • SJR Hirsch-Index (2019): 87
  • SJR Quartile Score (2019): Q3 Condensed Matter Physics
  • SJR Quartile Score (2019): Q3 Physical and Theoretical Chemistry
  • Impact Factor (2018): 2.471
  • Scimago Journal Rank (2018): 0.634
  • SJR Hirsch-Index (2018): 78
  • SJR Quartile Score (2018): Q2 Condensed Matter Physics
  • SJR Quartile Score (2018): Q2 Physical and Theoretical Chemistry

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
4
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)