Authors:
Bruno Alves Rocha Laboratório de Pesquisa, Desenvolvimento & Inovação (P, D & I), Apis Flora Industrial e Comercial LTDA, Rua: Triunfo, 945, 14020-670, Ribeirão Preto, SP, Brazil

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Marina Rezende Rodrigues Laboratório de Pesquisa, Desenvolvimento & Inovação (P, D & I), Apis Flora Industrial e Comercial LTDA, Rua: Triunfo, 945, 14020-670, Ribeirão Preto, SP, Brazil

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Paula Carolina Pires Bueno Laboratório de Pesquisa, Desenvolvimento & Inovação (P, D & I), Apis Flora Industrial e Comercial LTDA, Rua: Triunfo, 945, 14020-670, Ribeirão Preto, SP, Brazil

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Ana Rita de Mello Costa-Machado Laboratório de Pesquisa, Desenvolvimento & Inovação (P, D & I), Apis Flora Industrial e Comercial LTDA, Rua: Triunfo, 945, 14020-670, Ribeirão Preto, SP, Brazil

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Mirela Mara de Oliveira Lima Leite Vaz Laboratório de Pesquisa, Desenvolvimento & Inovação (P, D & I), Apis Flora Industrial e Comercial LTDA, Rua: Triunfo, 945, 14020-670, Ribeirão Preto, SP, Brazil

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Andresa Piacezzi Nascimento Laboratório de Pesquisa, Desenvolvimento & Inovação (P, D & I), Apis Flora Industrial e Comercial LTDA, Rua: Triunfo, 945, 14020-670, Ribeirão Preto, SP, Brazil

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Hernane Silva Barud Instituto de Química, UNESP, Rua Francisco Degni s/n, Quitandinha, 14800-900, Araraquara, SP, Brazil

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Andresa Aparecida Berretta-Silva Laboratório de Pesquisa, Desenvolvimento & Inovação (P, D & I), Apis Flora Industrial e Comercial LTDA, Rua: Triunfo, 945, 14020-670, Ribeirão Preto, SP, Brazil

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Abstract

The propolis produced in Southeastern Brazil is known as green propolis (BGP) because of its color and the most important plant source is Baccharis dracunculifolia. Several authors reported biological activities such as antiulcer, anti-inflammator, antimutagenic, antifungal/antibacterial, antileishmanial/antiplasmodial for the BGP. For this reason, BGP has been extensively employed in food and beverages, thus helping improve health and preventing diseases. Some authors related that the biological activities of BGP are mostly due to its high levels of prenylated ρ-coumaric acids derivatives, mainly artepillin C. The inclusion complex between Brazilian green propolis (BGP) with hydroxypropyl-β-cyclodextrin (HP-β-CD) was prepared and its characterization was investigated by different analytical techniques (X-ray diffraction, Fourier transform infrared spectroscopy, and thermogravimetry) and suggesting that propolis was molecularly dispersed in the HP-β-CD matrix. The increasing solubility of chemical constituents was determined using quantitation methods for total flavonoids and polyphenols. Furthermore, it was developed a method for the quantitation and identification of the main compounds by high-performance liquid chromatography in order to evaluate the increasing water solubility of each constituent in aqueous BGP extract (aromadendrin, isosakuranetin, and artepillin C). The antioxidant activity was evaluated by chemical assay 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging.

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
1
Issues
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24
Founder Akadémiai Kiadó
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H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
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CH-6330 Cham, Switzerland Gewerbestrasse 11.
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Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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