Geopolymers
Inorganic polymeric new materials
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Manrong Tan
Manrong Tan
China Military Institute of Chinese Materia Medica, 302 Military Hospital of China, 100 West 4th Ring Middle Road, Beijing 100 039, People's Republic of China
Pharmacy College, Jiangxi University of TCM, Nanchang 330 004, People's Republic of China pharmcy302@126.com
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Pharmacy College, Jiangxi University of TCM, Nanchang 330 004, People's Republic of China pharmcy302@126.com
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Yongsheng Ren
Yongsheng Ren
China Military Institute of Chinese Materia Medica, 302 Military Hospital of China, 100 West 4th Ring Middle Road, Beijing 100 039, People's Republic of China
Pharmacy College, Chengdu University of TCM, Chengdu 610 075, People's Republic of China
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Pharmacy College, Chengdu University of TCM, Chengdu 610 075, People's Republic of China
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Dan Yan
Dan Yan
China Military Institute of Chinese Materia Medica, 302 Military Hospital of China, 100 West 4th Ring Middle Road, Beijing 100 039, People's Republic of China
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Xianghong Meng
Xianghong Meng
The 309th Military Hospital of China, Beijing 100 094, People's Republic of China
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Longhu Chen
Longhu Chen
China Military Institute of Chinese Materia Medica, 302 Military Hospital of China, 100 West 4th Ring Middle Road, Beijing 100 039, People's Republic of China
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Lingling Qiu
Lingling Qiu
China Military Institute of Chinese Materia Medica, 302 Military Hospital of China, 100 West 4th Ring Middle Road, Beijing 100 039, People's Republic of China
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Yan Yan
Yan Yan
China Military Institute of Chinese Materia Medica, 302 Military Hospital of China, 100 West 4th Ring Middle Road, Beijing 100 039, People's Republic of China
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Jianyu Li
Jianyu Li
China Military Institute of Chinese Materia Medica, 302 Military Hospital of China, 100 West 4th Ring Middle Road, Beijing 100 039, People's Republic of China
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Xiaohe Xiao
Xiaohe Xiao
China Military Institute of Chinese Materia Medica, 302 Military Hospital of China, 100 West 4th Ring Middle Road, Beijing 100 039, People's Republic of China
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Abstract
A challenging method for sterility test which was rapid and reliable had been established to assess the adaptability and robustness of the microbial under different conditions. There were material and energy metabolism or exchange with microbial on microcalorimetry, as a result this method can be served as one of the optimization of thermodynamics sterility test. Thermal power-time curves under various environmental conditions (including processing temperature, storage time, and drugs inhibition) were determined. Typical microbial growth thermal power-time curves were obtained. The curves were analyzed qualitatively and quantitatively by similarity values of bio-profiles and thermodynamics parameters, such as the exponential growth rate constant (k), detection time (Td). The similarity showed that microbial growth curves of low processing temperature, short storage time (1 month), and Traditional Chinese Medicine injection (Shuanghuanglian, contained native compounds) inhibiting were match better with the normal than other circumstance. Thermodynamic parameters indicated that the microcalorimetric method could detect the positive bacteria within 18 h (less than 10 cfu), and more quickly identify the different states of the bacterium growth and metabolism than routine sterility. In conclusion, characterized by of the specific and strong two-dimensional information, microcalorimetry could supply thermograms as biological profiles to describe the microbial activity under different conditions, which were not only used as a rapid and reliable identification of microbial, but also as a method for sterility test of microcalorimetry optimization.
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| Journal of Thermal Analysis and Calorimetry | |
|---|---|
| Language | English |
| Size | A4 |
| Year of Foundation |
1969 |
| Volumes per Year |
1 |
| Issues per Year |
24 |
| Founder | Akadémiai Kiadó |
| Founder's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Publisher | Akadémiai Kiadó Springer Nature Switzerland AG |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. CH-6330 Cham, Switzerland Gewerbestrasse 11. |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 1388-6150 (Print) |
| ISSN | 1588-2926 (Online) |
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Temperature dependence of the rate of reaction in thermal analysis
The Arrhenius equation in condensed phase kinetics
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