Authors:
Zuzana Bujdošová Department of Inorganic Chemistry, P.J. Šafárik University, Moyzesova 11, 041 54, Kosice, Slovak Republic

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Katarína Győryová Department of Inorganic Chemistry, P.J. Šafárik University, Moyzesova 11, 041 54, Kosice, Slovak Republic

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Dagmar Mudroňová Department of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy, Komenského 73, 041 81, Kosice, Slovak Republic

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Daniela Hudecová Department of Biochemistry and Microbiology, Slovak Technical University, Radlinského 9, 812 37, Bratislava, Slovak Republic

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Jana Kovářová Institute of Macromolecular Chemistry, AS CR, Heyrovského nám. 2, 162 06, Prague 6, Czech Republic

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Abstract

New zinc(II) 4- and 5-chlorosalicylate complexes of general formula [Zn(X-sal)2(L)n(H2O)x] (where X-sal = 4-Clsalicylate, 5-Clsalicylate; L = N,N-diethylnicotinamide, isonicotinamide, theophylline; n = 1, 2; x = 0, 1, 2, 4) were prepared. The complexes were determined by elemental analysis and characterised by infrared spectroscopy. The thermal behaviour of the complexes was studied by simultaneous TG, DTG and DTA methods under dynamic air conditions. The thermal decomposition is a multi-step process. In the first step of the thermal decomposition, water is released in hydrated compounds. The anhydrous compounds start to decompose by the release of organic ligand, followed by chlorosalicylic acid, chlorophenol and carbon monoxide. The final solid product of the thermal decomposition is zinc oxide. The volatile products of the thermal decomposition were determined by mass spectrometry. The antimicrobial activities of the complexes were evaluated against selected pathogen and probiotic bacteria, yeasts and fungi strains. Bioactivities of the tested compounds are different against bacteria, yeasts and filamentous fungi. It was found that bacteria were more sensitive to the studied zinc(II) complex compounds than yeasts or filamentous fungi.

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
1
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
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Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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