Journal of Thermal Analysis and Calorimetry
Volume/Issue:
Volume 110: Issue 3
Thermodynamic properties of resveratrol in dimethyl sulfoxide
Authors:
Z. X. Li Department of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji 721013, Shaanxi, China

Search for other papers by Z. X. Li in
Current site
Google Scholar
PubMed Close
,
W. W. Zhao Department of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji 721013, Shaanxi, China

Search for other papers by W. W. Zhao in
Current site
Google Scholar
PubMed Close
, and
X. H. Pu Department of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji 721013, Shaanxi, China

Search for other papers by X. H. Pu in
Current site
Google Scholar
PubMed Close
Pages:
1249–1252
Online Publication Date:
17 Nov 2011
Publication Date:
01 Dec 2012
Article Category:
Research Article
DOI:
https://doi.org/10.1007/s10973-011-2013-8
Keywords:
Enthalpy of dissolution; DMSO; Kinetics; Resveratrol; Thermodynamics
Restricted access

Abstract

In this article, the enthalpies of dissolution of resveratrol in dimethyl sulfoxide (DMSO) were measured using a RD496-2000 Calvet microcalorimeter at 298.15 K under atmospheric pressure. The differential enthalpy (ΔdifHm) and molar enthalpy (ΔsolHm) of dissolution of resveratrol in DMSO were determined, and the relationship between heat and the amount of solute was also established. Based on the thermodynamic and kinetic knowledge, the corresponding kinetic equation, half-life, ΔsolHm, ΔsolSm, ΔsolGm, the relative partial molar enthalpy (ΔsolHm(partial)) and the relative apparent molar enthalpy (ΔsolHm(app)) of the dissolution process were obtained. The results showed that this study not only provided a simple method for the determination of the half-life for a drug, but also offered a theoretical reference for the clinical application of resveratrol.

  • 1.

    Philipp, S, Akos, S, Walter, J, Thomas, S. 2008. Resveratrol and its analogs: Defense against cancer, coronary disease and neurodegenerative maladies or just a fad?. Mutat Res. 658:68–94 .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 2.

    Wu, D, Jin, ZX, Xu, XW, Zhu, SJ. 2011. Effects of resveratrol on platelet function in rats with severe acute pancreatitis. J Hepatopancreatobiliary Surg. 23:26–28 (in chinese).

    • Search Google Scholar
    • Export Citation
  • 3.

    Li, YJ, Zhang, R, Wang, X, Zhao, J. 2011. Study on in vitro anti-dermatophytes activity of resveratrol. Chin Gen Pract. 14:892–893.

  • 4.

    Auriekson NQ , Bruno AQG, Waldir MM Jr, RSB. A theoretical antioxidant pharmacophore for resveratrol. Eur J Med Chem. 2009; 44: 1644–9.

  • 5.

    Robert, EK, Kyle, DK, Joshua, AB. 2005. Resveratrol reduces oxidation and proliferation of human retinal pigment epithelial cells via extracellular signal-regulated kinase inhibition. Chem Biol Interact. 151:143–149 .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 6.

    Özer, S, Abdullah, S, Ayliz, VO, Şule, Ç, Nursal, G, Berrak, ÇY, Göksel, Ş. 2007. Resveratrol improves ifosfamide-induced fanconi syndrome in rats. Toxicol Appl Pharmacol. 222:33–41 .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 7.

    Ji, H, Wu, YZ, Ji, Q. 2011. Physiological effects and application prospects of resveratro. China J Mod Med. 21:1625–1629.

  • 8.

    Sun, XJ, Xu, XY, Liu, M, Li, LW, Sun, DZ. 2010. Enthalpic interactions of anti-tumor drug matrine in aqueoussodium chloride solutions. J Therm Anal Calorim. 100:1073–1077 .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 9.

    Montgomery, RL, Melaugh, RA, Lau, CC, Meier, GH, Chan, HH, Rossini, FD. 1977. Determination of the energy equivalent of a water solution calorimeter with a standard substance. J Chem Thermodyn. 9:915–936 .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10.

    Xue, L, Zhao, FQ, Xing, XL. 2009. Dissolution properties of 1,3,3-trinitroazetidine in ethyl acetate and N,N-dimethylformamide. Acta Phys Chim Sin. 25:2413–2416.

    • Search Google Scholar
    • Export Citation
  • 11.

    Gao, SL, Chen, SP, Hu, RZ, Li, HY, Shi, QZ. 2002. Derivation and application of theromodynamic equations. Chin J Inorg Chem. 18:362–366 (in chinese).

    • Search Google Scholar
    • Export Citation
  • Collapse
  • Expand
Cover Journal of Thermal Analysis and Calorimetry
Journal of Thermal Analysis and Calorimetry
Print ISSN:
1388-6150
Online ISSN:
1572-8943

To see the editorial board, please visit the website of Springer Nature.

Manuscript Submission: HERE

For subscription options, please visit the website of Springer Nature.

Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation		 1969
Volumes
per Year		 1
Issues
per Year		 24
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Mar 2024 33 0 0
Apr 2024 8 0 0
May 2024 3 0 0
Jun 2024 20 0 0
Jul 2024 5 0 0
Aug 2024 23 0 0
Sep 2024 2 0 0