Author:
F. I. Khattab Analytical Chemistry Department, Faculty of Pharmacy Cairo University Cairo Egypt

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The thermal behaviour of some antiallergic drugs belonging to different groups of antihistaminics, such as phenyltoloxamine, chlorpromazine, clemizole and meclozine was examined. Thermogravimetry, derivative thermogravimetry and differential thermal analysis curves were used for the elucidation of the mechanisms of thermal decomposition. The melting temperatures of the compounds and their thermal stabilities were determined. The stability was found to decrease in the order: clemizole > chlorpromazine > meclozine > phenyltoloxamine.

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
1
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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