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  • 1 Istituto per la Chimica di Molecole di Interesse Biologico C. N. R. Via Toiano 6 80072 Arco Felice-Napoli
  • | 2 Dipartimento di Chimica dell'Università “Federico II” di Napoli Via Mezzocannone 4 80134 Napoli Italy
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Crystal structures together with enthalpies and temperatures of fusion of two substituted amino acids, N-acetylsarcosinamide (NASarA) and N-acetyl-L-isoleucinamide (NAIA), were determined by single crystal X-ray analysis and differential scanning calorimetry, respectively. The results were compared with those of some analogous amino acid derivatives previously studied. The detailed knowledge of crystallographic parameters is undoubtedly useful for discussing the thermodynamic results and rationalizing the fusion behaviour, owing to the rather poor knowledge of the molecular interactions occurring in the melt.

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