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  • 1 Universidade de Coimbra Faculdade de Farmácia 3000 Coimbra 3000 Coimbra
  • | 2 Universidade de Coimbra Departamento de Química, Faculdade de Ciencias e Tecnologia 3000 Coimbra Portugal 3000 Coimbra Portugal
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Abstract  

Several samples of terfenadine prepared by crystallization from different solvents under different experimental conditions were studied. The DSC curves obtained at a heating rate of 1C min−1 afforded the temperature of melting and the mole fractions of the components of each sample. Certain of the samples were composed of two solid phases mixed in molar ratios varying between nearly one and a single structural form. Three polymorphic forms were identified.

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