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Abstract  

When the DSC analysis of different samples of terpin hydrate is carried out, a non identified small endotherm is observed at about 100°C, just before the melting endotherm. This phenomenon is detected whatever the experimental conditions are.After some trials, this endotherm was identified as an eutectic formed with terpin hydrate and desolvated terpin (17/83).The importance of the experimental conditions is preponderant. In an open pan, the desolvation occurs and the melting endotherm of the anhydrous form can be observed at 105°C. In a closed pan, no desolvation is detected and the melting endotherm at 120°C is that of the terpin hydrate.The eutectic exhibits a good compression ability and a fast dissolution. Its stability is correct. Its use in therapeutic tablets can be envisaged.The eutectic structure could be, more generally, favourable to compression owing to the isotropic texture of this particular solid state.

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  • Impact Factor (2019): 2.731
  • Scimago Journal Rank (2019): 0.415
  • SJR Hirsch-Index (2019): 87
  • SJR Quartile Score (2019): Q3 Condensed Matter Physics
  • SJR Quartile Score (2019): Q3 Physical and Theoretical Chemistry
  • Impact Factor (2018): 2.471
  • Scimago Journal Rank (2018): 0.634
  • SJR Hirsch-Index (2018): 78
  • SJR Quartile Score (2018): Q2 Condensed Matter Physics
  • SJR Quartile Score (2018): Q2 Physical and Theoretical Chemistry

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
4
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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