The results of recent developments on modelling of supramolecular ordering and physicochemical properties of molecular mixtures
have been reviewed. The main attention is paid to the unified approach based on a generalized quasichemical model for a set
of thermodynamic, dielectric and optical properties of mixtures, self-organized by specific bonding. Interrelations between
thermodynamic, as well as dielectric, and optical properties of liquid mixtures, reflecting different molecular parameters,
and the characteristics of quasichemical processes are presented. Applications for thermodynamic functions of mixing, permittivity,
coefficients Rayleigh light scattering in molecular mixtures are considered. Data on thermodynamics of aggregation in mixtures
have been obtained.