Journal of Thermal Analysis and Calorimetry
Volume/Issue:
Volume 67: Issue 3
The Action of the Selenomorpholine Compounds on Escherichia coli Growth by Microcalorimetry
Authors:
Li Xi

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Liu Yi Wuhan University Department of Chemistry, College of Chemistry and Environment Science Wuhan 430072 P. R. China Wuhan 430072 P. R. China

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Wu Jun Wuhan University Department of Chemistry, College of Chemistry and Environment Science Wuhan 430072 P. R. China Wuhan 430072 P. R. China

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Liang Huigang Wuhan University Department of Chemistry, College of Chemistry and Environment Science Wuhan 430072 P. R. China Wuhan 430072 P. R. China

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Qu Songsheng Wuhan University Department of Chemistry, College of Chemistry and Environment Science Wuhan 430072 P. R. China Wuhan 430072 P. R. China

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Pages:
589–595
Online Publication Date:
25 Oct 2004
Publication Date:
01 Mar 2002
Article Category:
Research Article
DOI:
https://doi.org/10.1023/a:1014392418707
Keywords:
effect; Escherichia coli ; metabolism; microcalorimetry; selenomorpholine; thermokinetics
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Abstract  

The action of three kinds of the selenomorpholine compounds on a strain ofEscherichia coli was studied by microcalorimetry. Differences in their capacities to affect the metabolism of this bacterium were observed. The extent and duration of the effect on the metabolism as judged from the rate constant (k) of Escherichia coli (in log phase) varied with the different drugs. The kinetics show that selenomorpholine compounds had an effect on the metabolism process of Escherichia coli. The k of Escherichia coli in the presence of the drugs increased with the increasing concentrations of the drugs (C) at low concentration; but at high concentration, the rate constant decreased with the increasing concentrations of the drugs. The experimental results reveal that the sequence of antibiotic activity of selenomorpholines is: N-selenomorpholinemethyl succinimide and its hydrochloride>N-(α-selenomorpholinebenzyl) succinimide.

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Cover Journal of Thermal Analysis and Calorimetry
Journal of Thermal Analysis and Calorimetry
Print ISSN:
1388-6150
Online ISSN:
1572-8943

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation		 1969
Volumes
per Year		 1
Issues
per Year		 24
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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