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  • 1 Universidade de Coimbra Departamento de Química, Faculdade de Cięncias e Tecnologia 3004-535 Coimbra Portugal 3004-535 Coimbra Portugal
  • | 2 Universidade de Coimbra Faculdade de Farmácia 3000-295 Coimbra Portugal 3000-295 Coimbra Portugal
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Abstract  

Terfenadine samples prepared by crystallization in different media and supersaturation conditions were used to investigate the polymorphism of the substance. The study was based on DSC melting curves. An empirical parametric equation was used for modelling the experimental data. The signal recorded was resolved into the corresponding overlapping peak components by fitting analysis. Four polymorphic phases were identified.

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