Authors:
C. G. Mothé Departament of Organic Process, School of Chemistry, Federal University of Rio de Janeiro 21949-900, RJ, Brazil

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T. Carestiato Departament of Organic Process, School of Chemistry, Federal University of Rio de Janeiro 21949-900, RJ, Brazil

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M. B. Aguila Laboratory of Morphometry and Cardiovascular Morphology, State University of Rio de Janeiro 20551-030, RJ, Brazil

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C. A. Mandarim-de-Lacerda Laboratory of Morphometry and Cardiovascular Morphology, State University of Rio de Janeiro 20551-030, RJ, Brazil

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Summary Hypertension is a major and growing public health problem. It is responsible for the mortality of millions of people around world, and is increasing each year. Nevertheless, the understanding of the relationship between the composition of the heart's cells, hypertension and health diseases is still very incomplete. The present study focuses on the evaluation of the attributes of some hearts of Spontaneous Hypertension Rats (SHR), comparing with SHR which received additional amounts of polysaccharide (SHR+P) and with wistar rats (normal blood pressure) by Thermal Analysis. Some differences could be seen between groups, as the residue content after 800°C was different for rats from different groups, and of wistar rats hearts samples showed 5.3±0.3& of residues vs. 8.3±1.5& of the SHR. DSC profiles for wistar rats showed one intense endothermic event at 160°C, with enthalpy transition of 450 J g-1 and more three small events. Thermal analyses curves also showed some differences between freezing and no freezing samples, probably associated to the denaturation of proteins and degradation of organic materials.

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
1
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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