Arthritis of major joints, especially osteoarthritis of the knee is a very frequent disease of human beings mainly in the
developed countries. The pathology of osteoarthritis has been subject of many publications before, using a wide spectrum of
different methods to evaluate degenerative changes of hyaline cartilage. The authors examined osteoarthritic human knee joint
hyaline cartilage with differential scanning calorimetry. The different stages of cartilage degeneration have been verified
by histological examinations. The research group demonstrated thermal differences between various stages of osteoarthritis.
Besides explaining possible causes for experienced thermodynamic effects, the authors reflect upon future research ways and
the possibilities of applying the method in practice.