Authors:
Anita Kovács Department of Pharmaceutical Technology, University of Szeged Eötvös Str. 6, 6720 Szeged, Hungary Eötvös Str. 6, 6720 Szeged, Hungary

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I. Csóka Department of Pharmaceutical Technology, University of Szeged Eötvös str. 6, 6720 Szeged, Hungary Eötvös str. 6, 6720 Szeged, Hungary

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Magdolna Kónya Department of Pharmaceutical Technology, University of Szeged Eötvös str. 6, 6720 Szeged, Hungary Eötvös str. 6, 6720 Szeged, Hungary

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E. Csányi Department of Pharmaceutical Technology, University of Szeged Eötvös str. 6, 6720 Szeged, Hungary Eötvös str. 6, 6720 Szeged, Hungary

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A. Fehér Department of Pharmaceutical Technology, University of Szeged Eötvös str. 6, 6720 Szeged, Hungary Eötvös str. 6, 6720 Szeged, Hungary

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I. Erős Department of Pharmaceutical Technology, University of Szeged Eötvös str. 6, 6720 Szeged, Hungary Eötvös str. 6, 6720 Szeged, Hungary

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The properties of the inner and the external aqueous phases, were studied in w/o/w multiple emulsions with light microscopic image analysis and differential scanning calorimetry (DSC). The importance of multiple emulsions lies in the presence of these aqueous phases, making them available for sustained, controlled drug delivery systems. Differentiation of these two aqueous phases, studying the effect of manufacturing technology on droplet structure, quantitative determination of phase volumes and any changes occurring during storage are essential when planning w/o/w emulsions. The present study uses microscopic observations combined with DSC measurements in order to identify the formed structure, at developmental stage in case of different components, preparation methods, and stirring rates. These tools are beneficial during manufacturing as in process controls, or to ensure product quality.

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
1
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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