Authors:
A. Fehér Department of Pharmaceutical Technology, University of Szeged Eötvös Str. 6, 6720 Szeged, Hungary Eötvös Str. 6, 6720 Szeged, Hungary

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E. Csányi Department of Pharmaceutical Technology, University of Szeged Eötvös Str. 6, 6720 Szeged, Hungary Eötvös Str. 6, 6720 Szeged, Hungary

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I. Csóka Department of Pharmaceutical Technology, University of Szeged Eötvös Str. 6, 6720 Szeged, Hungary Eötvös Str. 6, 6720 Szeged, Hungary

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Anita Kovács Department of Pharmaceutical Technology, University of Szeged Eötvös Str. 6, 6720 Szeged, Hungary Eötvös Str. 6, 6720 Szeged, Hungary

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I. Erős Department of Pharmaceutical Technology, University of Szeged Eötvös Str. 6, 6720 Szeged, Hungary Eötvös Str. 6, 6720 Szeged, Hungary

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The interactions between surfactant and water were studied thermoanalytically focusing on the lyotropic liquid crystalline and microemulsion region in four ternary systems containing Cremophor EL and Cremophor RH40 as surfactants, neutral oil and isopropyl myristate as oily components. Subzero temperature DSC (SZT-DSC) measurements were carried out to determine the quantity of the bound water forming a hydration layer in surfactant microstructures, and the amount of free water, which has physico-chemical properties not much different from those of pure water. The variation of the surfactant:bound water ratio in the function of water concentration was also investigated. Phase changes detected by the SZT-DSC measurements were confirmed by polarization-microscopic and rheological investigations.

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
1
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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