View More View Less
  • 1 Wuhan University of Technology School of Sciences Wuhan 430070 China
  • | 2 Wuhan University College of Chemistry and Molecular Science Wuhan 430072 China
  • | 3 Huazhong Agricultural University State key laboratory of agricultural microbiology Wuhan 430070 China
  • | 4 Wuhan University of Technology School of Material Science and Technology Wuhan 430070 China
Restricted access

Abstract  

The biological activity of a kind of hetero-bimetallic Schiff-base complex was studied using Escherichia coli (E. coli) cell as the target. By microcalorimetry, the difference of anti-bacterial activity between the binuclear Schiff-base and the ligand was determined and analyzed. To analyze the inhibition of the bacterial growth internally, the E. coli cells grown in the presence of hetero-bimetallic Schiff-base complex were observed by scanning electron microscopy. The images in high resolution revealed the damage of outer cell membrane caused the inhibitory effect on E. coli. Inductively coupled plasma-mass spectrometry results proved the absorption of the complex by cells, which confirmed the interaction between the Schiff-base and biological macromolecule.

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Jan 2021 0 0 0
Feb 2021 0 0 0
Mar 2021 0 0 0
Apr 2021 0 0 0
May 2021 0 0 0
Jun 2021 1 0 0
Jul 2021 0 0 0