Authors:
R. Filho Univ. Federal de Goiás-UFG Campus Samambaia LAMES-Laboratório de Métodos de Extração e Separação, Instituto de Química CEP 74001-970 Goiânia-GO Brasil

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P. Franco Univ. Federal de Goiás-UFG Campus Samambaia LAMES-Laboratório de Métodos de Extração e Separação, Instituto de Química CEP 74001-970 Goiânia-GO Brasil

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E. Conceição Univ. Federal de Goiás-UFG Faculdade de Farmácia Av. Universitária com 1a Avenida, S/N CEP 74605-220 Goiânia-GO Brazil

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M. Leles Univ. Federal de Goiás-UFG Campus Samambaia LAMES-Laboratório de Métodos de Extração e Separação, Instituto de Química CEP 74001-970 Goiânia-GO Brasil

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Abstract  

A formulation of nifedipine tablets was prepared in the present research. The tablets were conditioned in amber-colored glass containers and placed in a climatized room at 40°C and relative humidity of 75% for 180 days. Differential scanning calorimetry (DSC) and thermogravimetry (TG) were used in order to evaluate the thermal properties of nifedipine, the excipients and two well-known nifedipine degradation products. The results demonstrated that there is no evidence on the interaction between nifedipine and excipients, or degradation products.

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
1
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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