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  • 1 Univ. Federal de Goiás-UFG Campus Samambaia LAMES-Laboratório de Métodos de Extração e Separação, Instituto de Química CEP 74001-970 Goiânia-GO Brasil
  • | 2 Univ. Federal de Goiás-UFG Faculdade de Farmácia Av. Universitária com 1a Avenida, S/N CEP 74605-220 Goiânia-GO Brazil
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Abstract  

A formulation of nifedipine tablets was prepared in the present research. The tablets were conditioned in amber-colored glass containers and placed in a climatized room at 40°C and relative humidity of 75% for 180 days. Differential scanning calorimetry (DSC) and thermogravimetry (TG) were used in order to evaluate the thermal properties of nifedipine, the excipients and two well-known nifedipine degradation products. The results demonstrated that there is no evidence on the interaction between nifedipine and excipients, or degradation products.