Calorimetric measurement of adsorption enthalpies of native lysozyme(Lyz) on a moderately hydrophobic surface at 25°C, pH
7.0 and various salt concentrations was performed. Based on the thermodynamics of stoichiometric displacement theory (SDT),
we calculated the fractions of thermodynamic functions involving four subprocesses during a displacement adsorption process
from the directly determined enthalpies in combination with adsorption isotherm measurements. The thermodynamic fractions
reveal the relative degree of the four subprocesses for contributions to enthalpy, entropy and free energy. The results show
that native Lyz adsorption on a moderately hydrophobic surface is an entropy driven process contributed mainly by conformational
loss of adsorbed Lyz.