View More View Less
  • 1 University of Szeged, Faculty of Medicine Department of Orthopaedics Semmelweis u. 6 6725 Szeged Hungary
  • | 2 University of Szeged, Faculty of Pharmacy Department of Pharmaceutical Technology Eötvös u. 6 6720 Szeged Hungary
Restricted access

Abstract  

During recent years, knowledge of rheumatoid arthritis has increased, and management of the disease has improved. A limited number of papers have been published before on the subject of thermal analysis of degenerative cartilage but rheumatoid arthritis (RA) has not been studied previously. A new protocol had to be established before the investigation. The purpose of this study was to further characterize the altered metabolism in human RA cartilage that promotes disease progression. Previously, these methods have not been used for this purpose. The use of thermal analysis could be an effective method for controlling the relationship between biomarkers and disease progression.