Authors:
L. Manral Defence Research and Development Establishment (DRDE) Gwalior (M. P.) 474002 India

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P. Gupta Defence Research and Development Establishment (DRDE) Gwalior (M. P.) 474002 India

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M. Suryanarayana Defence Research and Development Establishment (DRDE) Gwalior (M. P.) 474002 India

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K. Ganesan Defence Research and Development Establishment (DRDE) Gwalior (M. P.) 474002 India

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R. Malhotra Defence Research and Development Establishment (DRDE) Gwalior (M. P.) 474002 India

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Abstract  

Flash pyrolysis of fentanyl and its analogues has been studied on pyrolysis-gas chromatograph-mass spectrometer (Py-GC-MS) system. Initial pyrolytic fragmentation of these compounds led to the formation of N-substituted-1,2,5,6-tetrahydropyridine and N-phenylpropanamide as the primary pyrolytic products. Moreover, depending up on the furnace temperature, these pyrolytic products can also undergo further fragmentation to give different compounds. We, herein, discuss the probable fragmentation routes of parent as well as pyrolytic products. This study will be useful while developing technologies for thermal aerosol generation of fentanyl and related compounds.

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Journal of Thermal Analysis and Calorimetry
Language English
Size A4
Year of
Foundation
1969
Volumes
per Year
1
Issues
per Year
24
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1388-6150 (Print)
ISSN 1588-2926 (Online)

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