Reaction Kinetics, Mechanisms and Catalysis
Volume/Issue:
Volume 106: Issue 2
A general process for the cyclization of aminoalcohols to the corresponding amines over Cu–Cr–La/γ-Al2O3
Authors:
Zhiwei Wu School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, People's Republic of China

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Fan Yang School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, People's Republic of China

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Huabang Wang School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, People's Republic of China

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Jianchao Ma School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, People's Republic of China

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Ligong Chen School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, People's Republic of China

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Yang Li School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, People's Republic of China

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Pages:
485–493
Online Publication Date:
19 Apr 2012
Publication Date:
01 Aug 2012
Article Category:
Research Article
DOI:
https://doi.org/10.1007/s11144-012-0447-z
Keywords:
Heterocycle; Amino alcohol; Cyclization; Cu–Cr–La/γ-Al2O3 catalyst
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Abstract

A general process for the cyclization of aminoalcohols to the corresponding amines over Cu–Cr–La/γ-Al2O3 is established in a continuous fixed-bed reactor. The catalyst was characterized by XRD, XPS and NH3-TPD. The doped Cr is found to improve the copper particle dispersion. The addition of La neutralized the strong acid sites and decreased the amount of the acid sites, which facilitated the desorption of amino compounds on the surface of catalysts and inhibited the carbon deposition. Under the optimum conditions, the yields of pyrrolidine, piperidine and piperazine were 99.5, 99.5 and 98.6 %, in order, while the yields of hexahydro-1H-azepine and homopiperazine were 46.5 and 32.7 % due to the unstable seven-membered ring by the cyclization of the corresponding aminoalcohols over Cu–Cr–La/γ-Al2O3.

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Cover Reaction Kinetics, Mechanisms and Catalysis
Reaction Kinetics, Mechanisms and Catalysis
Print ISSN:
1878-5190
Online ISSN:
1878-5204

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Reaction Kinetics, Mechanisms and Catalysis
Language English
Size B5
Year of
Foundation		 1974
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Issues
per Year		 6
Founder Akadémiai Kiadó
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Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
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Springer Nature Switzerland AG
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ISSN 1878-5190 (Print)
ISSN 1878-5204 (Online)

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