Analysis of scientific production is made in the domains of vaccines for the period 1990–1995, including eight Iberian-American countries. To attain the results, different indicators were applied such as: collaboration rate, activity index and representation techniques, using a cluster analysis and multidimensional scaling. Similarities between countries are represented according to their activity index in the subject field. Results show a discontinuity in the scientific production over the years, where each country has a peculiar behavior.