Studies of university–industry collaboration remain subject to important limitations due to the shortage of empirical data
and a lack of consistency in that obtained to date. This article puts into practice a set of universities Third Mission indicators
in a regional innovation system. Selected indicators previously compiled from literature were reorganized and pre-tested.
We have undertaken two face-to-face surveys of 737 firms and 765 heads of research teams, respectively. The results test the
validation of indicators and provide a complex map of university–industry linkages as well as some observations on the flexibility
needed to address this issue.