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  • 1 Department of Inorganic Chemistry, Medical University of Lublin, Staszica 6, 20-081, Lublin, Poland
  • | 2 Department of Organic Chemistry, Medical University of Lublin, Staszica 6, 20-081, Lublin, Poland
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Summary

Some new derivatives of thiosemicarbazide and the 1,2,4-triazole of sulphanylacetic acid have been chromatographed on RP-18 HPTLC plates with mobile phases containing water and an organic modifier (methanol, dioxane, acetone, 2-propanol, or tetrahydrofuran). Relationships between solute retention and modifier concentration were described by Snyder's linear equation. The equation was used to determine RM0 values, by extrapolation, and the S values denoting the slopes of the relationship between linear retention and mobile phase concentration; both values characterize the lipophilicity of the substances. Calculated values of RM0 were correlated with log P values for the drugs investigated by use of the software HyperChem. Correlations between intercept (RM0) and slope (S) from the linear equations were also calculated. The effects of different mobile phase modifiers on experimentally obtained lipophilicity were also analysed and compared.

  • [1]. C. Hansch A. Leo D. Elkins 1971 Chem. Rev. 71 525.

  • [2]. F. Csizmadia A. Tsantili-Kakoulidou I. Panderi F. Darvas 1997 J. Pharm. Sci. 86 865871.

  • [3]. K. Jóźwiak H. Szumiło E. Soczewiński 2001 Wiad. Chem. 55 10471074.

  • [4]. E. Soczewiński A. Wachtmeister 1962 J. Chromatogr. 7 311320.

  • [5]. L.R. Snyder J.W. Dolan J.R. Gant 1979 J. Chromatogr. 165 3.

  • [6]. T. DjakoviĆ-SekuliĆ M. Ačanski N. Perišić-Janjić 2001 J. Chromatogr. B 766 6775.

  • [7]. A. Pyka 2004 J. Planar Chromatogr. 17 275279.

  • [8]. J. Flieger M. Tatarczak M. Wujec M. Pitucha H. Szumiło 2006 J. Planar Chromatogr. 19 3241.

  • [9]. N. Perišić-Janjić T. Djaković-Sekulić L. Jevrić B. Jovanović 2005 J. Planar Chromatogr. 18 212216.

  • [10]. T. Djaković-Sekulić C. Sârbu N. Perišić-Janjić 2005 J. Planar Chromatogr. 18 432436.

  • [11]. P. Kastner M. Kuchař J. Klimeš D. Dosedlová 1997 J. Chromatogr. A 766 165170.

  • [12]. J. Sochacka A. Kowalska 2006 J. Planar Chromatogr. 19 307312.

  • [13]. P. Kastner J. Klimeš P. Velenovská V. Klimešová 2002 J. Planar Chromatogr. 15 200203.

  • [14]. J. Veličković Tešić D. Milojković-Opsenica 2005 J. Planar Chromatogr. 18 358363.

  • [15]. V.N. Viswanadhan A.K. Ghose G.N. Revankar R.K. Robins 1989 J. Chem. Inf. Comput. Sci. 29 163.

  • [16]. N. Sadlej-Sosnowska I. Śledzińska 1992 J. Chromatogr. 595 5361.

  • [17]. H.H. Jaffe 1953 Chem. Rev. 53 191196.

  • [18]. L.R. Snyder and J.J. Kirkland, Introduction to Modern Liquid Chromatography, Wiley, 1979, p, 286.

  • [19]. G.L. Biagi A.M. Barbaro A. Sapone 1994 J. Chromatogr. A 662 341361.

  • [20]. J. Flieger B. Modzelewska-Banachiewicz H. Szumiło M. Tatarczak 2004 Chromatographia 60 S291S294.

  • [21]. T. Sławik C. Kowalski 2002 J. Chromatogr. A 952 295299.

  • [22]. Cs. Horváth W. Melander I. Molnár 1976 J. Chromatogr. 125 129.

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Senior editors

Editor(s)-in-Chief: Kowalska, Teresa

Editor(s)-in-Chief: Sajewicz, Mieczyslaw

Editors(s) Danica Agbaba (University of Belgrade, Belgrade, Serbia);
Ivana Stanimirova-Daszykowska (University of Silesia, Katowice, Poland),
Monika Waksmundzka-Hajnos (Medical University of Lublin, Lublin, Poland)

Editorial Board

R. Bhushan (The Indian Institute of Technology, Roorkee, India)
J. Bojarski (Jagiellonian University, Kraków, Poland)
B. Chankvetadze (State University of Tbilisi, Tbilisi, Georgia)
M. Daszykowski (University of Silesia, Katowice, Poland)
T.H. Dzido (Medical University of Lublin, Lublin, Poland)
A. Felinger (University of Pécs, Pécs, Hungary)
K. Glowniak (Medical University of Lublin, Lublin, Poland)
B. Glód (Siedlce University of Natural Sciences and Humanities, Siedlce, Poland)
K. Kaczmarski (Rzeszow University of Technology, Rzeszów, Poland)
H. Kalász (Semmelweis University, Budapest, Hungary)
I. Klebovich (Semmelweis University, Budapest, Hungary)
A. Koch (Private Pharmacy, Hamburg, Germany)
Ł. Komsta (Medical University of Lublin, Lublin, Poland)
P. Kus (Univerity of Silesia, Katowice, Poland)
D. Mangelings (Free University of Brussels, Brussels, Belgium)
E. Mincsovics (Corvinus University of Budapest, Budapest, Hungary)
G. Morlock (Giessen University, Giessen, Germany)
J. Sherma (Lafayette College, Easton, PA, USA)
R. Skibiński (Medical University of Lublin, Lublin, Poland)
B. Spangenberg (Offenburg University of Applied Sciences, Germany)
T. Tuzimski (Medical University of Lublin, Lublin, Poland)
Y. Vander Heyden (Free University of Brussels, Brussels, Belgium)
A. Voelkel (Poznań University of Technology, Poznań, Poland)
B. Walczak (University of Silesia, Katowice, Poland)
W. Wasiak (Adam Mickiewicz University, Poznań, Poland)

KOWALSKA, TERESA
E-mail: kowalska@us.edu.pl

SAJEWICZ, MIECZYSLAW
E-mail:msajewic@us.edu.pl

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2019  
Total Cites
WoS
495
Impact Factor 1,418
Impact Factor
without
Journal Self Cites
1,374
5 Year
Impact Factor
0,936
Immediacy
Index
0,460
Citable
Items
50
Total
Articles
50
Total
Reviews
0
Cited
Half-Life
6,2
Citing
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8,3
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0,00048
Article Influence
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0,164
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in
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100,00
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0,05895
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Percentile
20,349
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226/167=1,4
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Scopus
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41%

 

Acta Chromatographica
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Acta Chromatographica
Language English
Size A4
Year of
Foundation
1992
Publication
Programme
2021 Volume 33
Volumes
per Year
1
Issues
per Year
4
Founder Institute of Chemistry, University of Silesia
Founder's
Address
PL-40-007 Katowice, Poland, Bankowa 12
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-6290 (Print)
ISSN 2083-5736 (Online)

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