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  • 1 Department of Pharmaceutical Analysis, School of Pharmacy, Guiyang Medical University, Guiyang, 550004, China
  • | 2 Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, Shanghai, 201203, China
  • | 3 Department of Pharmacology, School of Medicine, Wuhan University, Wuhan, 430071, China
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Summary

Radix Isatidis has widely useful activities including anti-virus, anti-bacterial. Tryptanthrin, indigo, and indirubin are active ingredients in R. Isatidis. Response surface methodology (RSM)-optimized infrared-assisted extraction (IRAE) was developed and combined with HPLC for simultaneous determination of tryptanthrin, indigo, and indirubin from R. Isatidis. IRAE were investigated through extraction yields of the three components and optimized by RSM. The optimum conditions were as follows: infrared power of 129 W, solid/liquid ratio of 1:40 g/mL, and irradiation time of 22.5 min. IRAE conditions obtained by RSM were not only accurate, but also had practical value reflecting the expected optimization. Subsequently, this novel IRAE method was evaluated by extraction yield of the components of R. Isatidis samples from different regions. Compared with common extraction methods including maceration extraction (ME), reflux extraction (RE), ultrasound-assisted extraction (UAE), and microwave-assisted extraction (MAE), IRAE showed higher yield with advantages of no limitation of solvent selection, low cost, convenience under optimum extraction conditions. These results suggested the potential of RSM-optimized IRAE for extraction and analysis of the water-/fat-soluble compositions of Chinese herbal medicine. A simple chromatographic separation for simultaneous determination of tryptanthrin, indigo, and indirubin from Chinese herbal medicine R. Isatidis was performed on a C18 column (Diamonsil 150 mm × 4.6 mm i.d., 5 μm) with a mobile phase isocratic consisting of methanol and water at a flow-rate of 0.8 mL min−1. The retention times of tryptanthrin, indigo, and indirubin were 15.4, 31.9, and 58.6 min, respectively. The linear equations were obtained as follows: y = −3094.5744 + 21208.792x for tryptanthrin (R = 0.9998, 0.9–18.0 μg mL−1), y = 4730.0448 + 30180.567x for indigo (R = 0.9997, 0.5–10.0 μg mL−1) and y = −6582.9045 + 67069.312x for indirubin (R = 0.9997, 0.4–8.0 μg mL−1). The result showed that RSM-optimized IRAE was a simple, efficient pretreatment method for the analysis of complex matrix.

  • [1]. W.J. Kong Y.L. Zhao L.M. Shan X.H. Xiao W.Y. Guo 2008 J. Chromatogr. B 871 109114.

  • [2]. W. Zhou X.Y. Zhang M.F. Xie Y.L. Chen Y. Li G.L. Duan 2010 Chromatographia 72 719724.

  • [3]. S.H. Nian M. Liu 2005 J. Huaihai Med. 23 428429.

  • [4]. C.L. Wang J.L. Liu X.L. Shen 2007 Chemistry Online 70 8995.

  • [5]. L.F. Fan L.T. Zhang Z.F. Yuan H.J. Xu W. He 2008 Chin. J. Pharm. Anal. 28 540543.

  • [6]. J.E. Dong M.G. Gong Z.S. Liang 2007 J. Northwest A&F Univ. (Nat Sci Ed) 35 215218.

  • [7]. H. Ni X. Shi Y.H. Liu 2008 J. Qiqihar Med. College 29 1610.

  • [8]. L.X. Sun H. Tang P. Yin L.L. Ning K.S. Bi 2000 J. Shenyang Pharm. Univ. 17 191192.

  • [9]. C.Y. Li L.J. Zeng 2005 Res. Prac. Chin. Med. 19 5154.

  • [10]. H. Sun H.T. Lv Y.M. Zhang X.C. Meng J.T. Sui X.J. Wang K.S. Bi 2007 J. Sep. Sci. 30 31203126.

  • [11]. Y.F. Sha S. Shen G.L. Duan 2004 J. Pharm. Biomed. Anal. 36 381385.

  • [12]. B. Chen Y.J. Yu L. Gui T. Zhou G.L. Duan 2008 Fudan Univ. J. Med. Sci. 35 142144.

  • [13]. C.H. Deng J. Ji N. Li Y.J. Yu G.L. Duan X.M. Zhang 2006 J. Chromatogr. A 1117 115120.

  • [14]. Y.F. Sha C.H. Deng Z. Liu T.M. Huang B. Yang G.L. Duan 2004 J. Chromatogr. B 806 271276.

  • [15]. Y.J. Yu T.M. Huang B. Yang X. Liu G.L. Duan 2007 J. Pharm. Biomed. Anal. 43 2431.

  • [16]. X.L. Wang L.Q. Yan 2007 China Pharm. 18 2119.

  • [17]. P. Zou Y. Hong H.L. Koh 2005 J. Pharm. Biomed. Anal. 38 514520.

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Senior editors

Editor(s)-in-Chief: Kowalska, Teresa

Editor(s)-in-Chief: Sajewicz, Mieczyslaw

Editors(s) Danica Agbaba (University of Belgrade, Belgrade, Serbia);
Ivana Stanimirova-Daszykowska (University of Silesia, Katowice, Poland),
Monika Waksmundzka-Hajnos (Medical University of Lublin, Lublin, Poland)

Editorial Board

R. Bhushan (The Indian Institute of Technology, Roorkee, India)
J. Bojarski (Jagiellonian University, Kraków, Poland)
B. Chankvetadze (State University of Tbilisi, Tbilisi, Georgia)
M. Daszykowski (University of Silesia, Katowice, Poland)
T.H. Dzido (Medical University of Lublin, Lublin, Poland)
A. Felinger (University of Pécs, Pécs, Hungary)
K. Glowniak (Medical University of Lublin, Lublin, Poland)
B. Glód (Siedlce University of Natural Sciences and Humanities, Siedlce, Poland)
K. Kaczmarski (Rzeszow University of Technology, Rzeszów, Poland)
H. Kalász (Semmelweis University, Budapest, Hungary)
I. Klebovich (Semmelweis University, Budapest, Hungary)
A. Koch (Private Pharmacy, Hamburg, Germany)
Ł. Komsta (Medical University of Lublin, Lublin, Poland)
P. Kus (Univerity of Silesia, Katowice, Poland)
D. Mangelings (Free University of Brussels, Brussels, Belgium)
E. Mincsovics (Corvinus University of Budapest, Budapest, Hungary)
G. Morlock (Giessen University, Giessen, Germany)
J. Sherma (Lafayette College, Easton, PA, USA)
R. Skibiński (Medical University of Lublin, Lublin, Poland)
B. Spangenberg (Offenburg University of Applied Sciences, Germany)
T. Tuzimski (Medical University of Lublin, Lublin, Poland)
Y. Vander Heyden (Free University of Brussels, Brussels, Belgium)
A. Voelkel (Poznań University of Technology, Poznań, Poland)
B. Walczak (University of Silesia, Katowice, Poland)
W. Wasiak (Adam Mickiewicz University, Poznań, Poland)

KOWALSKA, TERESA
E-mail: kowalska@us.edu.pl

SAJEWICZ, MIECZYSLAW
E-mail:msajewic@us.edu.pl

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2020
 
Total Cites
650
WoS
Journal
Impact Factor
1,639
Rank by
Chemistry, Analytical 71/83 (Q4)
Impact Factor
 
Impact Factor
1,412
without
Journal Self Cites
5 Year
1,301
Impact Factor
Journal
0,34
Citation Indicator
 
Rank by Journal
Chemistry, Analytical 75/93 (Q4)
Citation Indicator
 
Citable
45
Items
Total
43
Articles
Total
2
Reviews
Scimago
28
H-index
Scimago
0,316
Journal Rank
Scimago
Chemistry (miscellaneous) Q3
Quartile Score
 
Scopus
393/181=2,2
Scite Score
 
Scopus
General Chemistry 215/398 (Q3)
Scite Score Rank
 
Scopus
0,560
SNIP
 
Days from
58
sumbission
 
to acceptance
 
Days from
68
acceptance
 
to publication
 
Acceptance
51%
Rate

2019  
Total Cites
WoS
495
Impact Factor 1,418
Impact Factor
without
Journal Self Cites
1,374
5 Year
Impact Factor
0,936
Immediacy
Index
0,460
Citable
Items
50
Total
Articles
50
Total
Reviews
0
Cited
Half-Life
6,2
Citing
Half-Life
8,3
Eigenfactor
Score
0,00048
Article Influence
Score
0,164
% Articles
in
Citable Items
100,00
Normalized
Eigenfactor
0,05895
Average
IF
Percentile
20,349
Scimago
H-index
26
Scimago
Journal Rank
0,255
Scopus
Scite Score
226/167=1,4
Scopus
Scite Score Rank
Chemistry (miscellaneous) 240/398 (Q3)
Scopus
SNIP
0,494
Acceptance
Rate
41%

 

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Acta Chromatographica
Language English
Size A4
Year of
Foundation
1992
Publication
Programme
2021 Volume 33
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per Year
1
Issues
per Year
4
Founder Institute of Chemistry, University of Silesia
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PL-40-007 Katowice, Poland, Bankowa 12
Publisher Akadémiai Kiadó
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ISSN 0236-6290 (Print)
ISSN 2083-5736 (Online)

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