Department of Radiology and Oncotherapy, Faculty of Medicine, Semmelweis University, Budapest, Hungary
Üllői út 78/a, H-1082, Budapest, Hungary
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Abstract
Improving survival rates and quality of life following modern combined cancer treatments have resulted in a growing number of patients requesting maintenance of reproductive functions. Few methods are currently available to maintain fertility during oncotherapy. Even though most of them are still experimental and their efficacy and safety have not been determined, the future for fertility preservation in women with cancer is promising. In vitro fertilization with embryo cryopreservation offers an established method, but it could be risky to delay cancer treatment regarding the progression of several cancer types. Moreover, exposure to a high estrogen milieu during ovarian stimulation is undesirable when patients have estrogen sensitive malignant tumors. Cryopreservation of mature oocytes following in vitro fertilization and intracytoplasmatic sperm injection offers advantages, but it is still limited due to its low success rate. Emerging techniques of ovarian tissue cryopreservation followed by autotransplantation have been clinically explored. Novel technologies of tissue freezing and thawing promise improving results. This procedure can be offered in the future for prepubertal girls before cancer treatment to maintain future fertility. Gonadal tissue cryopreservation and transplantation should be considered experimental in humans for the present time until greater evidence regarding efficacy and safety is accrued.
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| Clinical and Experimental Medical Journal | |
|---|---|
| Language | English |
| Size | |
| Year of Foundation |
2007 |
| Publication Programme |
ceased |
| Volumes per Year |
|
| Issues per Year |
|
| Publisher | Akadémiai Kiadó |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245 |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 2060-6249 (Print) |
| ISSN | 2060-968X (Online) |
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1st Congress of Fatty Liver and Metabolic Syndrome
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