Department of Human Morphology and Developmental Biology, Semmelweis University, Tűzoltó u. 58, H-1090, Budapest, Hungary
Search for other papers by Á. Nemeskéri in
Current site
Google Scholar
PubMed
Search for other papers by B. Matlakovics in
Current site
Google Scholar
PubMed
Search for other papers by I. Dudás in
Current site
Google Scholar
PubMed
Search for other papers by B. Molnár in
Current site
Google Scholar
PubMed
Search for other papers by A. Bartykowski in
Current site
Google Scholar
PubMed
Search for other papers by M. Kiss in
Current site
Google Scholar
PubMed
Search for other papers by I. Kristóf in
Current site
Google Scholar
PubMed
Search for other papers by K. Törő in
Current site
Google Scholar
PubMed
Search for other papers by K. Karlinger in
Current site
Google Scholar
PubMed
Abstract
In recent years, post mortem multi-slice computed tomography (MSCT) is increasingly applied for forensic and pathologic examination. However, classical dissection remains dominant in everyday practice. Lack of quantifiable data on the coronary system has become a disadvantageous attribute of traditional autopsy. Therefore, post mortem MSCT angiography was performed in 80 ex corpo hearts with the aim of improving the accuracy and quantitative documentation of pathologic and forensic diagnoses of coronary artery disease (CAD). Hearts were perfused by introducing a new oily or synthetic resin, or using both contrast materials successively. Then the perfused organs were processed for imaging. Detailed angiographic analysis enabled us to localize, map and quantify coronary calcifications, stenoses, and to characterize the types of atherosclerotic plaques. Significant early or late complications of widely used percutaneous coronary interventions (PCI) and coronary bypass surgery (CABS) could be revealed using CT analysis. Furthermore, by using our oily contrast material and CT imaging, we could identify and visualize the clinically important small caliber nodal arteries (diameter 0.4–2.0 mm). The present work suggests that post mortem CT angiography and post-processing of the data may improve the quality of pathologic and forensic diagnosis. Our collection of coronary casts including digital data are available for further analysis.
-
1. C. Jackowski S. Bolliger E. Aghayev A. Christe T. Kilchoer B. Aebi T. Périnat R. Dirnhofer M.J. Thali 2006 Reduction of post mortem angiography-induced tissue edema by using polyethylene glycol as a contrast materialdissolver J Forensic Sci 51 1134 1137.
-
2. F. Ovcina D. Cemerlic 1997 Clinical importance of intramural blood vessels in the sinoatrial segment of the conducting system of the heart Surg Radiol Anat 19 359 363.
-
3. G. Abuin A. Nieponice S. Martinez C. Fernando 2000 The role of atrial vessels in aortic root and mitral valve operations Ann Thorac Surg 70 4 1234 1237.
-
4. F. Saremi A. Abolhoda O. Ashikyan M.C. Jeffery N. Jagat G.V. Swaminatha K. Khushboo R. Aidan 2008 Arterial supply to sinoatrial and atrioventricular nodes: Imaging with Multidetector CT Radiology 246 99 107.
-
5. M. Barry 2003 Medical progress: Sudden death in young athletes N Engl J Med 349 1 20.
-
6. P. Angelini 2007 Coronary artery anomalies: An entity in search of an identity Circulation 115 1296 1305.
-
7. M. Von Ludinghausen 1975 Das verteilungs-muster der coronararterien und ihr einbau in das myokard. Ein beitrag zur. Funktionellen Anatomie der Herzkranzgefässe Dtsch Med Wochenschr. 100 2448 2451.
-
8. M. Loukas S. Bilinsky E. Bilinsky M. Petru R.H. Anderson 2009 The clinical anatomy of the coronary collateral circulation Clinical Anatomy 2 146 160.
-
9. S.M. Weman U.S. Salminen A. Penttilä A. Männikkö P.J. Karhunen 1999 Post mortem cast angiography in the diagnostics of graft complications in patients with fatal outcome following coronary artery bypass grafting (CABG) Int J Legal Med 112 107 114.
-
10. K. Törő M. Kiss V. Szarvas Nemeskéri I. Kristóf L. Magyar Keller 2007 Post mortem introduction of corrosion cast method after coronary stent implantation Forensic Science International 171 208 211.
-
11. A.S. Agatston W.R. Janowitz F.J. Hildner N.R. Zusmer M. Viamonte Jr. R. Detrano 1990 Quantification of coronary artery calcium using ultrafast computed tomography J Am Coll Cardiol 15 827 832.
-
12. B.R. Rah R.J. Katz A.G. Wasserman J.S. Reiner 2001 Post mortem three-dimensional reconstruction of the entire coronary arterial circulation using electron-beam computed tomography Circulation 104 3168.
-
13. K.J. Pfeifer U. Klein C.H. Chaussy C. Hammer K. Pielsticker H. Haendle J. Lissner 1974 Postmortale Nierenvergrößerungsangiographie mit fettlöslichem Kontrastmittel Fortschr Röntgenstr 121 472 476.
-
14. S. Kralev T.C. Poerner D. Basorth S. Lang C. Wolpert D. Haghi M. Borggrefe K.K. Haase T. Süselbeck 2006 Sidebranch occlusion after coronary stent implantation in patients presenting with ST-elevation myocardial infarction: Clinical impact and angigraphic predictors Am Heart J 151 153 157.
-
15. T. Timurkaynak H. Ciftci M. Ozdemir A. Cengel Y. Tavil M. Kaya G. Erdem M. Cemri O. Dortlemez H. Dortlemez 2002 Sidebranch occlusion after coronary stenting with or without balloon predilation: Direct versus conventional stenting J Invasive Cardiology 14 9 497 501.
-
16. H. Yilmaz I. Demir A. Belgi M. Kabukcu S. Yalcinkaya O. Sancaktar 2001 Sidebranch occlusion in direct intracoronary stenting: predictors and results Journal of Invasive Cardiology 13 578 581.
-
17. W. Mazur W.C. Grinstead A.H. Hakim S.F. Dabaghi J.M. Abukhalil N.M. Ali J. Joseph B.A. French A.E. Raizner 1994 Fate of sidebranches after intracoronary implantation of the Gianturco-Roubin Flex-Stent for acute or threatened closure after percutaneous transluminal coronary angioplasty Am J Cardiol 74 1207 1210.
-
18. M. Kotoku A. Tamura N.S.J. Kadota 2007 Sinus arrest caused by occlusion of the sinus node artery during percutaneous coronary intervention for lesions of the proximal right coronary artery Heart Vessels 22 389 92.
-
19. D. Berdajs L. Patonay M.I. Turina 2003 The clinical anatomy of the sinus node artery Ann Thorac Surg 76 732 736.
-
20. D. Berdajs U.P. Schurr A. Wagner B. Seifert M.I. Turina M. Genoni 2008 Incidence and pathophysiology of atrioventricular block following mitral valve replacement and ring annuloplasty European J Cardiothoracic Surgery 34 55 56.
-
21. G. Baroldi R. Bigi L. Cortigiani 2005 Ultrasound imaging versus morphopathology in cardiovascular diseases. Coronary collateral circulation and atherosclerotic plaque Cardiovascular Ultrasound 3 6.
-
22. E.A. Lo A. Dia A. Ndiaye M.L. Sow 1994 Anatomy of coronary arteries Dakar Medical 39 23 29.
-
23. P.B. Dobrin D. Hodgett T. Canfield R. Mrkvicka 2001 Mechanical determinants of graft kinking Annals of Vascular Surgery 15 343 349.
-
24. C.N.H. Enzweiler T.H. Wiesea J. Peterseina A.E. Lembckea A.C. Borgesc P. Dohmend U. Hoffmann B. Hamma 2003 Diameter changes of occluded venous coronary artery bypass grafts in electron beam tomography: preliminary findings European J Cardio-thoracic Surgery 23 347 353.
-
25. S. Goldman K. Zadina T. Moritz T. Ovitt G. Sethi J.G. Copeland L. Thottapurathu B. Krasnicka N. Ellis R.J. Anderson W. Henderson 2004 Long-term patency of saphenous vein and left internal mammary artery grafts after results from a Department of Veterans Affairs Cooperative Study J Am Coll Cardiol 44 2149 2156.
| 2019 | |
|---|---|
| Scimago H-index |
11 |
| Scimago Journal Rank |
0,220 |
| Scimago Quartile Score |
Medicine (miscellaneous) Q3 |
| Scopus Cite Score |
155/133=1,2 |
| Scopus Cite Score Rank |
General Medicine 199/529 (Q2) |
| Scopus SNIP |
0,343 |
| Scopus Cites |
206 |
| Scopus Documents |
23 |
| Interventional Medicine and Applied Science | |
|---|---|
| Language | English |
| Size | |
| Year of Foundation |
2009 |
| Publication Programme |
changed title |
| Volumes per Year |
|
| Issues per Year |
|
| Founder | Akadémiai Kiadó |
| Founder's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Publisher | Akadémiai Kiadó |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 2061-1617 (Print) |
| ISSN | 2061-5094 (Online) |
Monthly Content Usage
| Abstract Views | Full Text Views | PDF Downloads | |
|---|---|---|---|
| Nov 2024 | 33 | 0 | 0 |
| Dec 2024 | 15 | 0 | 0 |
| Jan 2025 | 41 | 0 | 0 |
| Feb 2025 | 45 | 0 | 0 |
| Mar 2025 | 42 | 0 | 0 |
| Apr 2025 | 21 | 0 | 0 |
| May 2025 | 1 | 0 | 0 |
Copyright Akadémiai Kiadó AKJournals is the trademark of Akadémiai Kiadó's journal publishing business branch.