Department of Neuroradiology, Universitätsklinikum Würzburg, Würzburg, Germany
Heart Center, Semmelweis University, Határőr út 18, H-1122, Budapest, Hungary
Search for other papers by Csanád Várallyay in
Current site
Google Scholar
PubMed
Search for other papers by György Balázs in
Current site
Google Scholar
PubMed
Search for other papers by Zsuzsanna Lénárd in
Current site
Google Scholar
PubMed
Search for other papers by Viktor Bérczi in
Current site
Google Scholar
PubMed
Search for other papers by Zorán Belics in
Current site
Google Scholar
PubMed
Search for other papers by Gábor Bajzik in
Current site
Google Scholar
PubMed
Search for other papers by Paul Wragg in
Current site
Google Scholar
PubMed
Search for other papers by Kálmán Hüttl in
Current site
Google Scholar
PubMed
Search for other papers by Ferenc Jolesz in
Current site
Google Scholar
PubMed
Abstract
Rationale and Objectives: MR-guided Focused Ultrasound Surgery (MRgFUS) is an evolving thermoablative technique for treatment of benign and malignant soft tissue tumors. The feasibility and effectiveness of this non-invasive method has been tested by several investigators by treating uterine fibroid. The aim of the present study was to evaluate early and mid-term efficacy of MRgFUS treatment using MR imaging follow-ups. Materials and Methods: 38 patients with uterine fibroids were enrolled and treated by MRgFUS in a single center. MRI follow-up exams were performed 3 and 6 months after the procedure. Total fibroid volumes (FV) and non-perfused volumes (NPV) were compared and evaluated over time. Results: There was a significant reduction of FV at 3- and 6-month follow-ups (10±19%, p=0.022 and 19±29%, p<0.001, respectively). In the subgroup of fibroids smaller than 5.4 cm in diameter a 35±18% volume reduction was found after 6 months. There was also a positive correlation found between the early NPV and the FV decrease at 3- and 6-months follow-ups. Conclusion: This study suggests that MRgFUS can effectively coagulate uterine fibroid tissue. Smaller UFs can be most effectively treated within reasonable time with the used equipment.
-
1. C.J. Wang et al.2006 Laparoscopic myomectomy for large uterine fibroids. A comparative study Surg Endosc 20 1427 1430.
-
2. N.A. Volkers et al.2006 Uterine artery embolization in the treatment of symptomatic uterine fibroid tumors (EMMY trial): periprocedural results and complications J Vasc Interv Radiol 17 471 480.
-
3. H.E. Cline et al.1992 MR-guided focused ultrasound surgery J Comput Assist Tomogr. 16 956 965.
-
4. K. Hynynen et al.2001 MR imaging-guided focused ultrasound surgery of fibroadenomas in the breast: a feasibility study Radiology 219 176 185.
-
5. F.A. Jolesz 2002 Hynynen K: Magnetic resonance image-guided focused ultrasound surgery Cancer J 8 Suppl1 S100 S112.
-
6. C.M. Tempany et al.2003 MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study Radiology 226 897 905.
-
7. J. Hindley et al.2004 MRI guidance of focused ultrasound therapy of uterine fibroids: early results AJR Am J Roentgenol 183 1713 1719.
-
8. E.A. Stewart et al.2003 Focused ultrasound treatment of uterine fibroid tumors: safety and feasibility of a noninvasive thermoablative technique Am J Obstet Gynecol 189 48 54.
-
9. O.C. Smart et al.2006 Magnetic resonance guided focused ultrasound surgery of uterine fibroids — the tissue effects of GnRH agonist pretreatment Eur J Radiol 59 163 167.
-
10. Y. Ishihara et al.1995 A precise and fast temperature mapping using water proton chemical shift Magn Reson Med 34 814 823.
-
11. P.R. Burn et al.2000 Uterine fibroleiomyoma: MR imaging appearances before and after embolization of uterine arteries Radiology 214 729 734.
-
12. A. Chapman G. Ter Haar 2007 Thermal ablation of uterine fibroids using MR-guided focused ultrasound — a truly non-invasive treatment modality Eur Radiol 17 2505 2511.
-
13. J. Rabinovici et al.2006 Pregnancy and live birth after focused ultrasound surgery for symptomatic focal adenomyosis: a case report Hum Reprod 21 5 1255 1259.
-
14. Z.M. Lénárd et al.2008 Uterine Leiomyomas: MR Imaging-guided Focused Ultrasound Surgery — Imaging Predictors of Success Radiology 249 187 194.
| 2019 | |
|---|---|
| Scimago H-index |
11 |
| Scimago Journal Rank |
0,220 |
| Scimago Quartile Score |
Medicine (miscellaneous) Q3 |
| Scopus Cite Score |
155/133=1,2 |
| Scopus Cite Score Rank |
General Medicine 199/529 (Q2) |
| Scopus SNIP |
0,343 |
| Scopus Cites |
206 |
| Scopus Documents |
23 |
| Interventional Medicine and Applied Science | |
|---|---|
| Language | English |
| Size | |
| Year of Foundation |
2009 |
| Publication Programme |
changed title |
| Volumes per Year |
|
| Issues per Year |
|
| Founder | Akadémiai Kiadó |
| Founder's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Publisher | Akadémiai Kiadó |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 2061-1617 (Print) |
| ISSN | 2061-5094 (Online) |
Monthly Content Usage
| Abstract Views | Full Text Views | PDF Downloads | |
|---|---|---|---|
| Oct 2024 | 37 | 0 | 0 |
| Nov 2024 | 35 | 1 | 2 |
| Dec 2024 | 17 | 0 | 0 |
| Jan 2025 | 14 | 0 | 0 |
| Feb 2025 | 16 | 0 | 0 |
| Mar 2025 | 16 | 0 | 0 |
| Apr 2025 | 0 | 0 | 0 |
Copyright Akadémiai Kiadó AKJournals is the trademark of Akadémiai Kiadó's journal publishing business branch.