Authors:
Fanni Gelley Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary
Department of Transplantation and Surgery, Semmelweis University, Baross u. 23–25, H-1082, Budapest, Hungary

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Attila Doros Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Tamás Micsik 1st Department of Pathology and Experimental Cancer Research, Budapest, Hungary

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János Fazakas Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Imre Fehérvári Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Gergely Zádori Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Zsófia Müller Department of Infectology, Saint George Hospital, Székesfehérvár, Hungary

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András Gelley Polyclinic of Hospitaller Brothers of Saint John of God, Budapest, Hungary

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Balázs Nemes Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Abstract

Adult-onset Still's disease is a rare systemic non-infectious inflammatory disease of unknown aetiology. It is characterized by high spiking fever, sore throat, arthralgia, transient maculopapular rash, hepatosplenomegaly, liver cytolysis, weight loss, leukocytosis, neutrophilia, lymphadenopathy, myopathia and polyserositis. Mild or moderate liver involvement is common but fulminate liver failure is a rare manifestation. We report a 41-year-old male with undiagnosed adult Still's disease who underwent liver transplantation due to acute fulminate liver failure. He died 6 months after the liver transplantation in a septic condition. To date, six patients with adult Still's disease-related liver failure have been reported who required liver transplantation. We emphasize that adult Still's disease should be considered in the differential diagnosis of fulminate liver failure, especially in young adults with fever of unknown aetiology or typical features in the history.

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2019  
Scimago
H-index
11
Scimago
Journal Rank
0,220
Scimago
Quartile Score
Medicine (miscellaneous) Q3
Scopus
Cite Score
155/133=1,2
Scopus
Cite Score Rank
General Medicine 199/529 (Q2)
Scopus
SNIP
0,343
Scopus
Cites
206
Scopus
Documents
23

 

Interventional Medicine and Applied Science
Language English
Size  
Year of
Foundation
2009
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 2061-1617 (Print)
ISSN 2061-5094 (Online)

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