Interventional Medicine and Applied Science
Volume/Issue:
Volume 3: Issue 2
West Nile virus encephalitis in kidney transplanted patient, first case in Hungary: Case report
Authors:
Anikó Smudla Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary
Department of Neurology, Semmelweis University, Budapest, Hungary
Department of Transplantation and Surgery, Semmelweis University, Baross utca 23, H-1082, Budapest, Hungary

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Zsuzsanna Gerlei Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Levente Gergely Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Marina Varga Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Éva Toronyi Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Attila Doros Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Tamás Mándli Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Zsuzsanna Arányi Department of Neurology, Semmelweis University, Budapest, Hungary

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Enikő Bán National Center for Epidemiology, Budapest, Hungary

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Enikő Sárváry Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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László Kóbori Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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János Fazakas Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Pages:
80–83
Online Publication Date:
01 Jun 2011
Publication Date:
01 Jun 2011
Article Category:
Research Article
DOI:
https://doi.org/10.1556/imas.3.2011.2.8
Keywords:
West Nile virus; encephalitis; kidney transplantation; intravenous immunoglobulin therapy; case report
Restricted access

Abstract

The complications caused by the rarely viral infections are more frequently treated in ICU (intensive care unit). The world paid attention to the WNV (West Nile virus) infections only in 1999, when 62 meningoencephalitis were registered in New York State. Six cases of WNV occur annually in Hungary. The authors present the first transplanted Hungarian patient with WNV encephalitis. The patient was hospitalized with epigastric pain, diarrhea, continuous fever, and decreasing amount of urine. The first checkup of infectious diseases was without any result. Although using of empirical antimicrobal therapy, the multiorgan failure patient remained febrile. On the basis of clinical signs, meningitis or encephalitis was suspected despite negative results of repeated cultures. On the 8th day, WNV infection was confirmed by serological examinations. With intravenous immunoglobulin therapy used within confines of supportive treatment, the patient became afebrile. After 21 days in ICU with good graft function, the patient was moved to the ward and he left the hospital after two more weeks. Until now, no prophylactic or etiological treatment has been developed for WNV. The early treatment is done with immunoglobulin or interferon; otherwise therapy has only supportive function. The disease caused by virus is more aggressive in transplanted patients and could be caused death.

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Cover Interventional Medicine and Applied Science
Interventional Medicine and Applied Science
Print ISSN:
2061-1617
Online ISSN:
2061-5094

2019  
Scimago
H-index		 11
Scimago
Journal Rank		 0,220
Scimago
Quartile Score		 Medicine (miscellaneous) Q3
Scopus
Cite Score		 155/133=1,2
Scopus
Cite Score Rank		 General Medicine 199/529 (Q2)
Scopus
SNIP		 0,343
Scopus
Cites		 206
Scopus
Documents		 23

 

Interventional Medicine and Applied Science
Language English
Size  
Year of
Foundation		 2009
Publication
Programme		 changed title
Volumes
per Year		  
Issues
per Year		  
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 2061-1617 (Print)
ISSN 2061-5094 (Online)

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