Interventional Medicine and Applied Science
Volume/Issue:
Volume 4: Issue 1
Non-anastomotic biliary strictures after liver transplantation: Focus on percutaneous treatment and extent of disease
Authors:
Attila Doros Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary
Department of Transplantation and Surgery, Semmelweis University, Baross u. 23, H-1082, Budapest, Hungary

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Pál Ákos Deák Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Erika Hartmann Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Andrea Németh Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Zsuzsa Gerlei Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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János Fazakas Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Dénes Görög Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Balázs Nemes Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Imre Fehérvári Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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László Kóbori Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

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Pages:
5–8
Online Publication Date:
01 Mar 2012
Publication Date:
01 Mar 2012
Article Category:
Research Article
DOI:
https://doi.org/10.1556/imas.4.2012.1.2
Keywords:
liver transplantation; biliary complication; percutaneous treatment; interventional radiology
Restricted access

Abstract

Introduction: Biliary strictures remain a key problem after liver transplantation. Anastomotic strictures are treated by surgery or interventional therapy. Intrahepatic stenosis requires retransplantation. For bridging, percutaneous and endoscopic interventions are used. The extent of the strictures may have an important role in therapy planning. Methods: Strictures were divided into four zones (1: extrahepatic, not included in this study; 2: hilar; 3: central; 4: peripheral). Twenty patients were treated with balloon dilatation/stent implantation/retransplantation/supportive care (Zone 1: 0/0/0/0; Zone 2: 8/7/2/0; Zone 3: 7/5/2/1; Zone 4: 1/1/3/1). Results: Mean follow-up time was 48 months. In Zone 2, one patient died as a result of recurrent hepatocellular carcinoma (HCC), and seven patients are alive, five after stent placements and two after retransplantation. Four patients are alive in Zone 3: all had stent placements and one later retransplantation. One patient died after retransplantation, two on the waiting list, and one due to chronic liver failure. One patient is alive in Zone 4 after early retransplantation, and three died. Conclusion: Percutaneous therapy is safe and effective in intrahepatic biliary stenosis after liver transplantation. It can provide the cure or bridge retransplantation. Based on zonal classification, we recommend the following treatments: Zone 4: early retransplantation; Zone 2: minimally invasive therapy; Zone 3: individual decisions.

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Cover Interventional Medicine and Applied Science
Interventional Medicine and Applied Science
Print ISSN:
2061-1617
Online ISSN:
2061-5094

2019  
Scimago
H-index		 11
Scimago
Journal Rank		 0,220
Scimago
Quartile Score		 Medicine (miscellaneous) Q3
Scopus
Cite Score		 155/133=1,2
Scopus
Cite Score Rank		 General Medicine 199/529 (Q2)
Scopus
SNIP		 0,343
Scopus
Cites		 206
Scopus
Documents		 23

 

Interventional Medicine and Applied Science
Language English
Size  
Year of
Foundation		 2009
Publication
Programme		 changed title
Volumes
per Year		  
Issues
per Year		  
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 2061-1617 (Print)
ISSN 2061-5094 (Online)

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