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Maria Carolina O. Rodrigues
Maria Carolina O. Rodrigues
Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, Tampa, FL, USA
Department of Internal Medicine, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, 12901 Bruce B. Downs Blvd., Tampa, FL, 33612, USA
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Department of Internal Medicine, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, 12901 Bruce B. Downs Blvd., Tampa, FL, 33612, USA
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Dmitriy Dmitriev
Dmitriy Dmitriev
Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, Tampa, FL, USA
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Antonio Rodrigues jr.
Antonio Rodrigues jr.
Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, Tampa, FL, USA
Department of Internal Medicine, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Department of Internal Medicine, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Loren E. Glover
Loren E. Glover
Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, Tampa, FL, USA
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Paul R. Sanberg
Paul R. Sanberg
Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, Tampa, FL, USA
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Julie G. Allickson
Julie G. Allickson
Cryo-Cell International, Inc., Tampa, FL, USA
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Nicole Kuzmin-Nichols
Nicole Kuzmin-Nichols
Saneron-CCEL Therapeutics Inc., Tampa, FL, USA
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Naoki Tajiri
Naoki Tajiri
Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, Tampa, FL, USA
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Kazutaka Shinozuka
Kazutaka Shinozuka
Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, Tampa, FL, USA
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Svitlana Garbuzova-Davis
Svitlana Garbuzova-Davis
Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, Tampa, FL, USA
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Yuji Kaneko
Yuji Kaneko
Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, Tampa, FL, USA
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Cesar V. Borlongan
Cesar V. Borlongan
Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, Tampa, FL, USA
Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, 12901 Bruce B. Downs Blvd., Tampa, FL, 33612, USA
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Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida, College of Medicine, 12901 Bruce B. Downs Blvd., Tampa, FL, 33612, USA
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Abstract
Cerebrovascular diseases are a major cause of death and long-term disability in developed countries. Tissue plasmin activator (tPA) is the only approved therapy for ischemic stroke, strongly limited by the short therapeutic window and hemorrhagic complications, therefore excluding most patients from its benefits. The rescue of the penumbra area of the ischemic infarct is decisive for functional recovery after stroke. Inflammation is a key feature in the penumbra area and it plays a dual role, improving injury in early phases but impairing neural survival at later stages. Stem cells can be opportunely used to modulate inflammation, abrogate cell death and, therefore, preserve neural function. We here discuss the possible role of stem cells derived from menstrual blood as restorative treatment for stroke. We highlight the availability, proliferative capacity, pluripotentiality and angiogenic features of these cells and explore their present and future experimental and clinical applications.
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| 2019 | |
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11 |
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0,220 |
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Medicine (miscellaneous) Q3 |
| Scopus Cite Score |
155/133=1,2 |
| Scopus Cite Score Rank |
General Medicine 199/529 (Q2) |
| Scopus SNIP |
0,343 |
| Scopus Cites |
206 |
| Scopus Documents |
23 |
| Interventional Medicine and Applied Science | |
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| Language | English |
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2009 |
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| Publisher | Akadémiai Kiadó |
| Publisher's Address |
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