Authors:
Rajesh Rajan Department of Cardiology Kerala Institute of Medical Sciences (KIMS), Trivandrum, Kerala State, 695029, India

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Peter K. Joseph Department of Cardiology Kerala Institute of Medical Sciences (KIMS), Trivandrum, Kerala State, 695029, India

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Vijayaraghavan Govindan Department of Cardiology Kerala Institute of Medical Sciences (KIMS), Trivandrum, Kerala State, 695029, India

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Abstract

Henoch-Schönlein purpura is an IgA-mediated, autoimmune, hypersensitivity vasculitis of childhood that results in a triad of symptoms, including a purpuric rash occurring on the lower extremities, abdominal pain or renal involvement, and arthritis. However, any of the triad may be absent, which often leads to a confusion in diagnosing the condition. Although the cause is unknown, Henoch-Schönlein purpura (HSP) is often associated with infectious agents, such as group A streptococci and mycoplasma. It has also been associated with food reactions, exposure to cold, insect bites, and drug allergies. The treatment is supportive and needs close followup of renal status. This report describes a rare presentation of Henoch-Schönlein purpura with coronary vasculitis which leads to myocardial infarction at the age of 53. Henoch-Schönlein purpura was diagnosed on the basis of no infection, accelerated ESR (35 mm/h), normal platelet count, positive skin biopsy, proteinuria, and negative searches for rheumatoid factor (RF), antinuclear antibody (ANA), antineutrophil cytoplasmic antibodies (ANCA), and anti-dsDNA.

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  • 2. S.D. Helander F.R. De Castro L.E. Gibson 1995 Henoch-Schönlein purpura: clinicopathologic correlation of cutaneous vascular IgA deposits and the relationship to leukocytoclastic vasculitis Acta Derm Venereol 75 125 129.

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  • 3. B.A. Michel G.G. Hunder D.A. Bloch L.H. Calabrese 1992 Hypersensitivity vasculitis and Henoch-Schönlein purpura: a comparison between the 2 disorders J Rheumatol 19 721 728.

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  • 4. D.A. Bloch B.A. Michel G.G. Hunder D.A. Bloch B.A. Michel G.G. Hunder D.J. McShane W.P. Arend L.H. Calabrese S.M. Edworthy A.S. Fauci J.F. Fries R.Y. Leavitt et al.1990 The American College of Rheumatology 1990 Criteria for the Classification of Vasculitis Patients and Methods Arthritis Rheum 33 1068.

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  • 5. J.A. Mills B.A. Michel D.A. Bloch et al.1990 The American College of Rheumatology criteria for the classification of Henoch-Schönlein purpura Arthritis Rheum 33 1114 1121.

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2019  
Scimago
H-index
11
Scimago
Journal Rank
0,220
Scimago
Quartile Score
Medicine (miscellaneous) Q3
Scopus
Cite Score
155/133=1,2
Scopus
Cite Score Rank
General Medicine 199/529 (Q2)
Scopus
SNIP
0,343
Scopus
Cites
206
Scopus
Documents
23

 

Interventional Medicine and Applied Science
Language English
Size  
Year of
Foundation
2009
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 2061-1617 (Print)
ISSN 2061-5094 (Online)

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