In an effort to utilize microfluidics to enable photochemistry, we have devised a method for fabrication of devices with UV-transmissive glass. The photochemical device is successfully incorporated into a system utilizing high-pressure capillary mercury lamps and cooling system. We have demonstrated the ability to carry out photochemical transformations with substantial rate acceleration. Furthermore, we highlight the ability to carry out analytical-scale reactions on a pulse flow automated system while modulating wavelength and residence time to identify optimal photochemical reaction conditions. The analytical conditions were also successfully converted to continuous-flow preparative scale.
1. Coxon, J. M.; Halton, B.Organic Photochemistry; Cambridge University Press: Cambridge, 1987.
Coxon, J. M.; Halton, B.Organic Photochemistry; Cambridge University Press: Cambridge, 1987.)| false