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  • 1 Institute of Chemistry, Karl-Franzens-University Graz, A-8010, Heinrichstrasse 28, Graz, Austria
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Abstract

In this section of the journal, the continuous flow chemistry literature of the preceding months is presented. The first part for the year 2012 includes articles published in the last 3 months of 2011. Some key examples are highlighted in the form of graphical abstracts. The remaining publications in the field are then listed grouped by journal name, with review articles grouped at the end.

  • “Conversion of glycerol to acrolein in the presence of WO3/TiO2 catalysts” A. Ulgen, W. F. Hoelderich Applied Catalysis A: General 2011, 400, 3438.

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  • Methanol dehydration to dimethyl ether in a platelet milli-reactor filled with H-ZSM5/SiC foam catalystY. Liu, S. Podila, D. L. Nguyen, D. Edouard, P. Nguyen, C. Pham, M. J. Ledoux, C. Pham-Huu Applied Catalysis A: General 2011, 409–410, 113121.

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  • “Transesterification of sunflower oil over MoO3 supported on alumina” T. M. Sankaranarayanan, A. Pandurangan, M. Banu, S. Sivasanker Applied Catalysis A: General 2011, 409–410, 239247.

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  • Continuous syntheses of highly dispersed composite nanocatalysts via simultaneous co-precipitation in supercritical waterX. Weng, J. Zhang, Z. Wu, Y. Liu, H. Wang, J. A. Darr Applied Catalysis B: Environmental 2011, 103, 453461.

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  • Continuous-flow synthesis of biaryls enabled by multistep solid-handling in a lithiation/borylation/Suzuki–Miyaura cross-coupling sequenceW. Shu, L. Pellegatti, M. A. Oberli, S. L. Buchwald Angewandte Chemie International Edition 2011, 50, 1066510669.

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  • Mechanism-performance relationships of metal oxides in catalyzed HCl oxidationA. P. Amrute, C. Mondelli, M. A. G. Hevia, J. Perez-Ramírez ACS Catalysis 2011, 1, 583590.

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  • Carbon nanotube-supported RuFe bimetallic nanoparticles as efficient and robust catalysts for aqueous-phase selective hydrogenolysis of glycerol to glycolsB. Li, J. Wang, Y. Yuan, H. Ariga, S. Takakusagi, K. Asakura ACS Catalysis 2011, 1, 15211528.

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  • Zeolite- and MgO-supported molecular iridium complexes: support and ligand effects in catalysis of ethene hydrogenation and H-D exchange in the conversion of H2 + D2J. Lu, P. Serna, B. C. Gates ACS Catalysis 2011, 1, 15491561.

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  • Production of propylene from 1-butene on highly active “Bi-functional single active site” catalyst: tungsten carbene-hydride supported on aluminaE. Mazoyer, K. C. Szeto, S. Norsic, A. Garron, J.-M. Basset, C. P. Nicholas, M. Taoufik ACS Catalysis 2011, 1, 16431646.

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  • Novel sol-gel lipases by designed bio-imprinting for continuous-flow kinetic resolutionsG. Hellner, Z. Boros, A. Tomin, L. Poppe Advanced Synthesis & Catalysis 2011, 353, 24812491.

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  • Ethene-induced temporary inhibition of Grubbs metathesis catalystsJ. Scholz, S. Loekman, N. Szesni, W. Hieringer, A. Görling, M. Haumann, P. Wasserscheid Advanced Synthesis & Catalysis 2011, 353, 27012707.

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  • “Translation of microwave methodology to continuous flow for the efficient synthesis of diaryl ethers via a base-mediated SNAr reaction” C. Wiles, P. Watts Beilstein Journal of Organic Chemistry 2011, 7, 13601371.

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  • Continuous preparation of carbon-nanotube-supported platinum catalysts in a flow reactor directly heated by electric currentA. Schlange, A. R. dos Santos, U. Kunz, T. Turek Beilstein Journal of Organic Chemistry 2011, 7, 14121420.

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  • Multistep flow synthesis of vinyl azides and their use in the copper-catalyzed Huisgen-type cycloaddition under inductive-heating conditionsL. Kupracz, J. Hartwig, J. Wegner, S. Ceylan, A. Kirschning Beilstein Journal of Organic Chemistry 2011, 7, 14411448.

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  • Continuous-flow enantioselective a-aminoxylation of aldehydes catalyzed by a polystyrene-immobilized hydroxyprolineX. C. Cambeiro, R. Martín-Rapún, P. O. Miranda, S. Sayalero, E. Alza, P. Llanes, M. A. Peric às Beilstein Journal of Organic Chemistry 2011, 7, 14861493.

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  • The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactorsK. A. Roper, H. Lange, A. Polyzos, M. B. Berry, I. R. Baxendale, S. V. Ley Beilstein Journal of Organic Chemistry 2011, 7, 16481655.

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  • Continuous proline catalysis via leaching of solid prolineS. M. Opalka, A. R. Longstreet, D. T. McQuade Beilstein Journal of Organic Chemistry 2011, 7, 16711679.

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  • Continuous-flow hydration–condensation reaction: Synthesis of a,b-unsaturated ketones from alkynes and aldehydes by using a heterogeneous solid acid catalystM. Rueping, T. Bootwicha, H. Baars, E. Sugiono Beilstein Journal of Organic Chemistry 2011, 7, 16801687.

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  • Liquid-phase catalytic transfer hydrogenation and cyclization of levulinic acid and its esters to g-valerolactone over metal oxide catalystsM. Chia, J. A. Dumesic Chemical Communications 2011, 47, 1223312235.

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  • Highly monodisperse conjugated polymer particles synthesized with drop-based microfluidicsA. J. C. Kuehne, D. A. Weitz Chemical Communications 2011, 47, 1237912381.

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  • In situ generation and intramolecular Schmidt reaction of keto azides in a microwave-assisted flow formatT. O. Painter, P. D. Thornton, M. Orestano, C. Santini, M. G. Organ, J. Aube Chemistry – A European Journal 2011, 17, 95959598.

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  • New insights into cyclobutenone rearrangements: A total synthesis of the natural ROS-generating anti-cancer agent Cribrostatin 6M. Mohamed, T. P. Goncalves, R. J. Whitby, H. F. Sneddon, D. C. Harrowven Chemistry – A European Journal 2011, 17, 1369813705.

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  • Continuous flow system with a polymer-supported dirhodium(II) catalyst: Application to enantioselective carbonyl ylide cycloaddition reactionsChemistry – A European Journal 2011, 17, 1399213998.

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  • Chemical synthesis of Helicobacter pylori lipopolysaccharide partial structures and their selective proinflammatory responsesA. Shimoyama, A. Saeki, N. Tanimura, H. Tsutsui, K. Miyake, Y. Suda, Y. Fujimoto, K. Fukase Chemistry – A European Journal 2011, 17, 1446414474.

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  • A single step methane conversion into synthetic fuels using microplasma reactorT. Nozaki, A. Agiral, S. Yuzawa, J. G. E. Han Gardeniers, K. Okazakia Chemical Engineering Journal 2011, 166, 288293.

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  • Suspension catalysis in a liquid-liquid capillary microreactorA. Ufer, D. Sudhoff, A. Mescher, D. W. Agar Chemical Engineering Journal 2011, 167, 468474.

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  • Enhanced production of ethyl pyruvate using gas-liquid slug flow in microchannelT. Yasukawa, W. Ninomiya, K. Ooyachi, N. Aoki, K. Mae Chemical Engineering Journal 2011, 167, 527530.

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  • “Novel Process Window for the safe and continuous synthesis of tert-butyl peroxy pivalate in a micro-reactor” T. Illg, V. Hessel, P. Löb, J. C. Schouten Chemical Engineering Journal 2011, 167, 504509.

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  • Fischer-Tropsch synthesis in microchannelsL. C. Almeida, F. J. Echave, O. Sanza, M. A. Centeno, G. Arzamendi, L. M. Gand ía, E. F. Sousa-Aguiar, J. A. Odriozola, M. Montes Chemical Engineering Journal 2011, 167, 536544.

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  • Hydrothermal micro continuous-flow synthesis of spherical, cylinder-, star- and flower-like ZnO microparticlesS. Li, G. A. Gross, P. M. Günther, J. M. Köhler Chemical Engineering Journal 2011, 167, 681687.

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  • Microfluidic synthesis of silica nanoparticles using polyethylenimine polymersP. He, G. Greenway, S. J. Haswell Chemical Engineering Journal 2011, 167, 694699.

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  • Production of unstable percarboxylic acids in a microstructured reactorF. Ebrahimi, E. Kolehmainen, P. Oinas, V. Hietapelto, I. Turunen Chemical Engineering Journal 2011, 167, 713717.

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  • Reaction and Raman spectroscopic studies of alcohol oxidation on gold-palladium catalysts in microstructured reactorsE. Cao, M. Sankar, S. Firth, K. F. Lam, D. Bethell, D. K. Knight, G. J. Hutchings, P. F. McMillan, A. Gavriilidis Chemical Engineering Journal 2011, 167, 734743.

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  • Bridging the gap: A nested-pipe reactor for slow reactions in continuous flow chemical synthesisC. B. Minnich, L. Greinera, C. Reimers, M. Uerdingen, M. A. Liauwa Chemical Engineering Journal 2011, 168, 759764.

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  • Design and experiments of a short-mixing-length baffled microreactor and its application to microfluidic synthesis of nanoparticlesC. K. Chung, T. R. Shih, C. K. Chang, C. W. Lai, B. H. Wu Chemical Engineering Journal 2011, 168, 790798.

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  • Synthesis of gold nanoparticles in an interdigital micromixer using ascorbic acid and sodium borohydride as reducersM. Luty-Błocho, K. Fitzner, V. Hessel, P. Löb, M. Maskos, D. Metzke, K. Pacławski, M. Wojnicki Chemical Engineering Journal 2011, 171, 279290.

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  • Comparative study of the synthesis of silica nanoparticles in micromixer-microreactor and batch reactor systemsL. Gutierrez, L. Gomez, S. Irusta, M. Arruebo, J. Santamaria Chemical Engineering Journal 2011, 171, 674683.

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  • Development of a gas-liquid microstructured system for oxidation of hydrogenated 2-ethyltetrahydroanthraquinoneJ. Tan, L. Du, Y. C. Lu, J. H. Xu, G. S. Luo Chemical Engineering Journal 2011, 171, 14061414.

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  • Paramagnetic ionic liquids as “liquid fixed-bed” catalysts in flow applicationV. Misuk, D. Breuch, H. Löwe Chemical Engineering Journal 2011, 173, 536540.

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  • Effect of gas and liquid flow rates on the size distribution of barium sulfate nanoparticles precipitated in a two phase flow capillary microreactorD. Jeevarathinam, A. K. Gupta, B. Pitchumani, R. Mohan Chemical Engineering Journal 2011, 173, 607611.

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  • Flash synthesis of carbohydrate derivatives in chaotic microreactorsY.-T. Chen, K.-H. Chen, W.-F. Fang, S.-H. Tsai, J.-M. Fang, J.-T. Yang Chemical Engineering Journal 2011, 174, 421424.

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  • Heterogeneously catalyzed synthesis of performic acid in a microstructured reactorF. Ebrahimi, E. Kolehmainen, I. Turunen Chemical Engineering Journal 2011, 179, 312317.

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  • Multiphase minireactor system for direct fluorination of ethylene carbonateP. Lang, M. Hill, I. Krossing, P. Woias Chemical Engineering Journal 2011, 179, 330337.

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  • Scale-up concept for modular microstructured reactors based on mixing, heat transfer, and reactor safetyN. Kockmann, D. M. Roberge Chemical Engineering and Processing: Process Intensification 2011, 50, 10171026.

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  • Single-phase fluid flow distribution and heat transfer in microstructured reactorsE. V. Rebrov, J. C. Schouten, M. H. J. M. de Croon Chemical Engineering Science 2011, 66, 13741393.

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  • Two-phase microfluidic flowsC.-X. Zhao, A. P. J. Middelberg Chemical Engineering Science 2011, 66, 13941411.

  • Nanoparticle synthesis in microreactorsC.-X. Zhao, L. He, S. Z. Qiao, A. P. J. Middelberg Chemical Engineering Science 2011, 66, 14631479.

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  • Gas–liquid and liquid–liquid mass transfer in microstructured reactorsM. N. Kashid, A. Renken, L. Kiwi-Minsker Chemical Engineering Science 2011, 66, 38763897.

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  • Direct conversion of methane in formaldehyde at very short residence timeJ. Zhang, V. Burkle-Vitzthum, P. M. Marquaire, G. Wild, J. M. Commenge Chemical Engineering Science 2011, 66, 63316340.

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  • Rate Acceleration of the Baylis–Hillman Reaction within MicroreactorsJ. Yang, L. Qi, J. Qiao, Y. Chen, H. Ma Chinese Journal of Chemistry 2011, 29, 23852388.

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  • The first case of competitive heterogeneously catalyzed hydrogenation using continuous-flow fixed-bed reactor system: hydrogenation of binary mixtures of activated ketones on Pt-alumina and on Pt-alumina-cinchonidine catalystsG. Szo˝llo˝si, Z. Makra, F. Fülöp, M. Bartók Catalysis Letters 2011, 141, 16161620.

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  • Intramolecular cyclisation of isosorbide by dimethylcarbonate chemistryP. Tundo, F. Arico, G. Gauthier, A. Baldacci Compets Rendus Chimie 2011, 14, 652655.

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  • Immobilised photosensitisers for continuous flow reactions of singlet oxygen in supercritical carbon dioxideX. Han, R. A. Bourne, M. Poliakoff, M. W. George Chemical Science 2011, 2, 10591067.

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  • Use of precatalysts greatly facilitate palladium-catalyzed alkynylations in batch and continuous-flow conditionsW. Shu, S. L. Buchwald Chemical Science 2011, 2, 23212325.

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  • Ethanol dehydration to ethylene in a stratified autothermal millisecond reactorM. J. Skinner, E. L. Michor, W. Fan, M. Tsapatsis, A. Bhan, L. D. Schmidt ChemSusChem 2011, 4, 11511156.

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  • High-quality diesel from hexose- and pentose-derived biomass platform moleculesA. Corma, O. de la Torre, M. Renz ChemSusChem 2011, 4, 15741577.

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  • Hydrodesulphurisation of 4,6-dimethyldibenzothiophene over NiMo catalysts supported on Ti(Al) modified MCM-41K. Jaroszewska, M. Lewandowski, J. R. Grzechowiak, B. Szyja Catalysis Today 2011, 176, 202207.

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  • Synthesis of (−)-Oseltamivir by using a microreactor in the Curtius rearrangementH. Ishikawa, B. P. Bondzic, Y. Hayashi European Journal of Organic Chemistry 2011, 60206031.

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  • “Efficient and ‘green’ microwave-assisted synthesis of haloalkylphosphonates via the Michaelis–Arbuzov reaction” P. Jansa, A. Holy, M. Dracinsky, O. Baszczynski, M. Cesnek, Z. Janeba Green Chemistry 2011, 13, 882888.

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  • Efficient enhancement of copper-pyridineoxazoline catalysts through immobilization and process designC. Aranda, A. Cornejo, J. M. Fraile, E. Garcıa-Verdugo, M. J. Gil, S. V. Luis, J. A. Mayoral, V. Martinez-Merino, Z. Ochoa Green Chemistry 2011, 13, 983990.

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  • “Continuous biocatalytic synthesis of (R)-2-octanol with integrated product separation” C. Kohlmann, S. Leuchs, L. Greiner, W. Leitner Green Chemistry 2011, 13, 14301436.

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  • Highly selective hydroformylation of long-chain alkenes in a supercritical fluid ionic liquid biphasic systemT. E. Kunene, P. B. Webb, D. J. Cole-Hamilton Green Chemistry 2011, 13, 14761481.

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  • Decision support towards agile eco-design of microreaction processes by accompanying (simplified) life cycle assessmentS. Huebschmann, D. Kralisch, H. Löwe, D. Breuch, J. H. Petersen, T. Dietrich, R. Scholz Green Chemistry 2011, 13, 16941707.

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  • A catalytic route to lower alcohols from glycerol using Ni-supported catalystsE. van Ryneveld, A. S. Mahomed, P. S. van Heerden, M. J. Green, H. B. Friedrich Green Chemistry 2011, 13, 18191827.

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  • Direct transformation of ethanol into ethyl acetate through catalytic membranes containing Pd or Pd-Zn: comparison with conventional supported catalystsA. B. Sanchez, N. Homs, S. Miachon, J.-A. Dalmon, J. L. G. Fierro, P. R. de la Piscina Green Chemistry 2011, 13, 25692575.

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  • Tungsten-Vanadium mixed oxides for the oxidehydration of glycerol into acrylic acidM. D. Soriano, P. Concepcion, J. M. L. Nieto, F. Cavani, S. Guidetti, C. Trevisanut Green Chemistry 2011, 13, 29542962.

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  • Silica-supported guanidine catalyst for continuous flow biodiesel productionJ. M. Balbino, E. W. de Menezes, E. V. Benvenutti, R. Cataluna, G. Ebeling, J. Dupont Green Chemistry 2011, 13, 31113116.

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  • JandaJel as a polymeric support to improve the catalytic efficiency of immobilized-1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) under solvent-free conditionsD. Lanari, R. Ballini, S. Bonollo, A. Palmieri, F. Pizzo, L. Vaccaro Green Chemistry 2011, 13, 31813186.

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  • Inhibition of gold and platinum catalysts by reactive intermediates produced in the selective oxidation of alcohols in liquid waterB. N. Zope, R. J. Davis Green Chemistry 2011, 13, 34833491.

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  • Microreactor system for high-pressure continuous flow homogeneous catalysis measurementsJ. Keybl, K. F. Jensen Industrial Engineering Chemistry Research 2011, 50, 1101311022.

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  • Step changes and deactivation behavior in the continuous decarboxylation of stearic acidA. T. Madsen, B. Rozmyszowicz, I. L. Simakova, T. Kilpiö, A.-R. Leino, K. Kordas, K. Eränen, P. Mäki-Arvela, D. Y. Murzin Industrial Engineering Chemistry Research 2011, 50, 1104911058.

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  • Modeling of toluene acetylation with acetic anhydride on H-USY zeoliteE. A. Dejaegere, J. W. Thybaut, G. B. Marin, G. V. Baron, J. F. M. Denayer Industrial Engineering Chemistry Research 2011, 50, 1182211832.

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  • Controllable preparation of poly(butyl acrylate) by suspension polymerization in a coaxial capillary microreactorZ. Liu, Y. Lu, B. Yang, G. Luo Industrial Engineering Chemistry Research 2011, 50, 1185311862.

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  • Methanol to gasoline-range hydrocarbons: influence of nanocrystal size and mesoporosity on catalytic performance and product distribution of ZSM-5A. A. Rownaghi, J. Hedlund Industrial Engineering Chemistry Research 2011, 50, 1187211878.

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  • Development of a photochemical microfluidics platformK. Pimparkar, B. Yen, J. R. Goodell, V. I. Martin, W.-H. Lee, J. A. Porco, Jr., A. B. Beeler, K. F. Jensen Journal of Flow Chemistry 2011, 1, 5355.

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  • An integrated synthesis–purification system to accelerate the generation of compounds in pharmaceutical discoveryJ. E. Hochlowski, P. A. Searle, N. P. Tu, J. Y. Pan, S. G. Spanton, S. W. Djuric Journal of Flow Chemistry 2011, 1, 5661.

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  • A continuous-flow system for asymmetric hydrogenation using supported chiral catalystsJ. Madarász, G. Farkas, S. Balogh, Á. Szöllo˝sy, J. Kovács, F. Darvas, L. Ürge, J. Bakos Journal of Flow Chemistry 2011, 1, 6267.

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  • Reissert indole synthesis using continuous-flow hydrogenationE. Colombo, P. Ratel, L. Mounier, F. Guillier Journal of Flow Chemistry 2011, 1, 6873.

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  • Cost analysis for a continuously operated fine chemicals production plant at 10 kg/day using a combination of microprocessing and microwave heatingF. Benaskar, A. Ben-Abdelmoumen, N. G. Patil, E.V. Rebrov, J. Meuldijk, L. A. Hulshof, V. Hessel, U. Krtschil, J. C. Schouten Journal of Flow Chemistry 2011, 1, 7489.

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  • White light emission from Mn-doped ZnSe d-dots synthesized continuously in microfluidic reactorsP. Shao, H. Wang, Q. Zhang, Y. Li Journal of Materials Chemistry 2011, 21, 1797217977.

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  • Flow reactor synthesis of CdSe, CdS, CdSe/CdS and CdSeS nanoparticles from single molecular precursor(s)A. L. Abdelhady, M. Afzaal, M. A. Malik, P. O'Brien Journal of Materials Chemistry 2011, 21, 1876818775.

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  • Synthesis and biochemical evaluation of D2-isoxazoline derivatives as DNA methyltransferase 1 inhibitorsS. Castellano, D. Kuck, M. Viviano, J. Yoo, F. Lopez-Vallejo, P. Conti, L. Tamborini, A. Pinto, J. L. Medina-Franco, G. Sbardella Journal of Medicinal Chemistry 2011, 54, 76637677.

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  • Porous photocatalytic membrane microreactor (P2M2): A new reactor concept for photochemistryH. C. Aran, D. Salamon, T. Rijnaarts, G. Mul, M. Wessling, R. G. H. Lammertink Journal of Photochemistry and Photobiology A: Chemistry 2011, 225, 3641.

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  • Determination of kinetic constants of a photocatalytic reaction in micro-channel reactors in the presence of mass-transfer limitation and axial dispersionG. Charles, T. Roques-Carmes, N. Becheikh, L. Falk, J.-M. Commenge, S. Corbel Journal of Photochemistry and Photobiology A: Chemistry 2011, 225, 202211.

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  • Meerwein–Ponndorf–Verley reduction of aldehydes formed in situ from a- and b-pinene epoxides in a supercritical fluid in the presence of aluminaI. V. Il'ina, S. Yu. Kurbakova, K. P. Volcho, N. F. Salakhutdinov, V. I. Anikeev Journal of Saudi Chemical Society 2011, 15, 313317.

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  • Small molecule library synthesis using segmented flowC. M. Thompson, J. L. Poole, J. L. Cross, I. Akritopoulou-Zanze, S. W. Djuric Molecules 2011, 16, 91619177.

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  • Enantioselective radical cyclisation reactions of 4-substituted quinolones mediated by a chiral templateA. Bakowski, M. Dressel, A. Bauer, T. Bach Organic & Biomolecular Chemistry 2011, 9, 35163529.

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  • Syntheses of mGluR5 PET radioligands through the radiofluorination of diaryliodonium tosylatesS. Telu, J.-H. Chun, F. G. Simeon, S. Lu, V. W. Pike Organic & Biomolecular Chemistry 2011, 9, 66296638.

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  • Perfluoroalkylation in flow microreactors: generation of perfluoroalkyllithiums in the presence and absence of electrophilesA. Nagaki, S. Tokuoka, S. Yamada, Y. Tomida, K. Oshiro, H. Amii, J.-i. Yoshida Organic & Biomolecular Chemistry 2011, 9, 75597563.

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  • Catalytic conversion of isopropanol and CO oxidation in presence of NiO supported on modified cordieriteS. A. El-Molla, G. A. El-Shobaky, Y. M. Fahmy, H. G. El-Shobaky The Open Catalysis Journal 2011, 4, 917.

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  • “Effects of ZnO and MoO3 doping on surface and catalytic properties of manganese oxide supported on alumina system” S. M. Ibrahim, G. A. El-Shobaky, G. M. Mohamed, N. A. Hassan The Open Catalysis Journal 2011, 4, 2735.

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  • The preparation of desflurane by the vapor-phase fluorination of isofluraneH. Sivaramakrishnan, A. A. Upare, D. Satagopan, O. R. Chambers Organic Process Research & Development 2011, 15, 585592.

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  • Controlled RAFT polymerization in a continuous flow microreactorC. H. Hornung, C. Guerrero-Sanchez, M. Brasholz, S. Saubern, J. Chiefari, G. Moad, E. Rizzardo, S. H. Thang Organic Process Research & Development 2011, 15, 593601.

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  • Continuous flow processing of slurries: evaluation of an agitated cell reactorD. L. Browne, B. J. Deadman, R. Ashe, I. R. Baxendale, S. V. Ley Organic Process Research & Development 2011, 15, 693697.

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  • A continuous-flow approach to palladium-catalyzed alkoxycarbonylation reactionsC. B. Kelly, C. Lee, M. A. Mercadante, N. E. Leadbeater Organic Process Research & Development 2011, 15, 717720.

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  • Fast scale-up using microreactors: pyrrole synthesis from micro to production scaleP. J. Nieuwland, R. Segers, K. Koch, J. C. M. van Hest, F. P. J. T. Rutjes Organic Process Research & Development 2011, 15, 783787.

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  • A scalable two-step continuous flow synthesis of nabumetone and related 4-aryl-2-butanonesM. Viviano, T. N. Glasnov, B. Reichart, G. Tekautz, C. O. Kappe Organic Process Research & Development 2011, 15, 858870.

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  • Adaptive process optimization for continuous methylation of alcohols in supercritical carbon dioxideR. A. Bourne, R. A. Skilton, A. J. Parrott, D. J. Irvine, M. Poliakoff Organic Process Research & Development 2011, 15, 932938.

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  • Development of an improved immobilized CAL-B for the enzymatic resolution of a key intermediate to OdanacatibM. D. Truppo, G. Hughes Organic Process Research & Development 2011, 15, 10331035.

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  • A versatile lab to pilot scale continuous reaction system for supercritical fluid processingU. Hintermair, C. Roosen, M. Kaever, H. Kronenberg, R. Thelen, S. Aey, W. Leitner, L. Greiner Organic Process Research & Development 2011, 15, 12751280.

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  • “Safe, convenient ortho-Claisen thermal rearrangement using a flow reactor” J. A. Rincon, M. Barberis, M. Gonzalez-Esguevillas, M. D. Johnson, J. K. Niemeier, W.-M. Sun Organic Process Research & Development 2011, 15, 14281432.

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  • Nitration chemistry in continuous flow using fuming nitric acid in a commercially available flow reactorC. E. Brocklehurst, H. Lehmann, L. La Vecchia Organic Process Research & Development 2011, 15, 14471453.

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  • UV initiated formation of polymer monoliths in glass and polymer microreactorsJ. A. Deverell, T. Rodemann, J. A. Smith, A. J. Canty, R. M. Guijt Sensors and Actuators B: Chemical 2011, 155, 388396.

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  • Clean and efficient benzylic C-H oxidation using a microflow systemX.-M. Lv, L.-J. Kong, Q. Lin, X.-F. Liu, Y.-M. Zhou, Y. Jia Synthetic Communications 2011, 41, 32153222.

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  • The continuous-flow synthesis of styrenes using ethylene in a palladium-catalyzed Heck cross-coupling reactionS. L. Bourne, P. Koos, M. O'Brien, B. Martin, B. Schenkel, I. R. Baxendale, S. V. Ley Synlett 2011, 26422647.

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  • Syngas-mediated C–C bond formation in flow: selective rhodium-catalyzed hydroformylation of styreneS. Kasinathan, S. L. Bourne, P. Tolstoy, P. Koos, M. O'Brien, R. W. Bates, I. R. Baxendale, S. V. Ley Synlett 2011, 26482651.

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  • “Synthesis of N-propynyl analogues of peptide nucleic acid (PNA) monomers and their use in the click reaction to prepare N-functionalized PNAs” N. M. Howarth, J. Ricci Tetrahedron 2011, 67, 95889594.

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  • Piecing together the puzzle: understanding a mild, metal free reduction method for the large scale synthesis of hydrazinesD. L. Browne, I. R. Baxendale, S. V. Ley Tetrahedron 2011, 67, 1026910303.

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  • Flow chemistry approach for partial deuteration of alkynes: synthesis of deuterated taxol side chainS. Chandrasekhar, B. V. D. Vijaykumar, B. M. Chandra, C. R. Reddy, P. Naresh Tetrahedron Letters 2011, 52, 38653867.

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  • Copper-catalyzed rearrangement of oximes into primary amidesS. K. Sharma, S. D. Bishopp, C. L. Allen, R. Lawrence, M. J. Bamford, A. A. Lapkin, P. Plucinski, R. J. Watson, J. M. J. Williams Tetrahedron Letters 2011, 52, 42524255.

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  • Application of flow chemistry to the reduction of nitriles to aldehydesJ. de M. Muñoz, J. Alcázar, A. de la Hoz, A. Díaz-Ortiz Tetrahedron Letters 2011, 52, 60586060.

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  • A continuous-flow synthesis of annulated and polysubstituted furans from the reaction of ketones and a-haloketonesM. York Tetrahedron Letters 2011, 52, 62676270.

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  • p-Iodinations in hydrocarbon media: continuous flow reactor application” D. W. Slocum, K. C. Tekin, Q. Nguyen, P. E. Whitley, T. K. Reinscheld, B. Fouzia Tetrahedron Letters 2011, 52, 71417145.

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  • Coupled chemo(enzymatic) reactions in continuous flowR. Yuryev, S. Strompen, A. Liese Beilstein Journal of Organic Chemistry 2011, 7, 14491467.

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  • The microwave-to-flow paradigm: translating high-temperature batch microwave chemistry to scalable continuous-flow processesT. N. Glasnov, C. O. Kappe Chemistry A European Journal 2011, 17, 1195611968.

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  • “(Bio)Catalytic continuous flow processes in scCO2 and/or ILs: towards sustainable (bio)catalytic synthetic platforms” P. Lozano, E. Garcia-Verdugo, S. V. Luis, M. Pucheault, M. Vaultier Current Organic Synthesis 2011, 810823.

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  • Enzyme-immobilized microfluidic process reactorsY. Asanomi, H. Yamaguchi, M. Miyazaki, H. Maeda Molecules 2011, 16, 60416059.

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  • Monolithic flow microreactors improve fine chemicals synthesisA. Sachse, A. Galarneau, B. Coq, F. Fajula New Journal of Chemistry 2011, 35, 259264.

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