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  • 1 Department of Chemistry, University of Hull, HU6 7RX Hull, UK
  • 2 Pfizer Global Research and Development, Sandwich, CT13 9NJ Kent, UK
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A highly scalable and efficient flow-system has been developed to perform the catalyzed acetylation of alcohols and phenols, such as salicylic acid, at room temperature in excellent yield. The volumetric throughput and the amount of product can be increased simply by increasing the diameter of a versatile catalytic 12-tungstosilicic acid-supported, silica monolith can be used to increase the quantity of product produced without having to changeing the optimal operatingreaction conditions.

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