Nicholas E. LeadbeaterDepartment of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, CT, 06269-3060, USA Department of Community Medicine and Health Care, University of Connecticut Health Center, The Exchange, 263 Farmington Ave, Farmington, CT, 06030, USA
A continuous-flow approach to the direct synthesis of arene chromium tricarbonyl complexes is presented. By working in flow mode, it is possible to avoid some of the problems of batch synthesis, especially sublimation of the Cr(CO)6 starting material and the competitive decomposition of the product during the lengthy reaction times. Heating at 220 °C and operating with a residence time of 10 min through the heated zone allows for the synthesis of (η6-C6H5CH3)Cr(CO)3 as an example, along with a selection of other (arene)Cr(CO)3 complexes.
1. For a recent review, see: Rosillo, M.; Domínguez, G.; Pérez-Castells, J.Chem. Soc. Rev. 2007, 36, 1589–1604.
For a recent review, see: Rosillo, M.; Domínguez, G.; Pérez-Castells, J.Chem. Soc. Rev. 2007, 36, 1589–1604.)| false
2. For an excellent collection of examples, see: Transition Metal Arene π-Complexes in Organic Synthesis and Catalysis (Topics in Organometallic Chemistry 7), Kündig, E. P., Ed.; Springer: Berlin, 2004.
3. For a review, see: Kündig, E. P. Top. Organomet. Chem.2004, 7, 3–20.
4. For a general procedure, see: Mahaffy, C. A. L.; Pauson, P. L.Inorg. Synth. 1990, 28, 136–140.
For a general procedure, see: Mahaffy, C. A. L.; Pauson, P. L.Inorg. Synth. 1990, 28, 136–140.)| false