Christopher (Xiang) LeeDepartment of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, CT, 06269-3060, USA

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Elizabeth A. PedrickDepartment of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, CT, 06269-3060, USA

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Nicholas E. LeadbeaterDepartment of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, CT, 06269-3060, USA
Department of Community Medicine and Health Care, University of Connecticut Health Center, The Exchange, 263 Farmington Ave, Farmington, CT, 06030, USA

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A continuous-flow approach to the direct synthesis of arene chromium tricarbonyl complexes is presented. By working in flow mode, it is possible to avoid some of the problems of batch synthesis, especially sublimation of the Cr(CO)6 starting material and the competitive decomposition of the product during the lengthy reaction times. Heating at 220 °C and operating with a residence time of 10 min through the heated zone allows for the synthesis of (η6-C6H5CH3)Cr(CO)3 as an example, along with a selection of other (arene)Cr(CO)3 complexes.

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Journal of Flow Chemistry
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