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  • 1 Department of Chemistry, Universidade Pontificia Catolica, Rio de Janeiro, Brazil
  • 2 Department of Bio-Nano Engineering, Shanghai Jiaotong University, Shanghai, China
  • 3 Department of Physics, Universidade Pontificia Catolica, Rio de Janeiro, Brazil
  • 4 Department of Chemistry, Università di Ferrara, Italy
  • 5 Department of Mathematics, Shanghai Jiaotong University, Shanghai, China
Open access

A novel micromixer concept for generation of concentration gradients, inspired by a Chinese design, the traditional Chinese knot “中国结”, which features a core mesh structure allowing for a very compact design, is presented. The new concept has been designed using modern computer-aided design (CAD) and computational fluid dynamics (CFD) simulation software and validated by performing multiple experiments. The final design is found to be significantly more compact than conventional ones and allows the use of up to 15 outlet channels.

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Supplementary Materials